Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11387 Bms-387032 GSE70138 HME1 Human 24h 1.11uM EID0014
Types Number Response transcription factors
Up-regulation 628 EGR1; SOX17; GATA2; JUN; EGR2; ESR1; RFX1; MEF2C; ZNF536; MYT1; FOS; CRX; THRB; NHLH2; ZNF711; NR5A1; MAK; GLI2; ZSCAN2; CDX4; HAND1; RFX3; VENTX; AFF3; WNT4; FOSB; NFKB2; ZNF816; ESR2; DMTF1; MLLT1; ZNF154; PCBD1; PRDM2; DYRK1B; ONECUT1; RSF1; AFF2; ZNF157; HNF4A; NFIX; PRDM9; SCAI; TFEC; AR; CARF; ZNF362; LZTR1; ZNF250; ZNF343; MAML3; HAND2; L3MBTL1; SOX3; GRIP1; SOX18; ZNF484; SUV39H2; ZNF770; MSX2; CREB5; HDAC9; HESX1; MAPK8IP1; PDX1; TBX6; ZNF407; RBPJL; ZNF749; ZNF613; ZNF814; HOXD12; NACA2; ZNF225; GCM2; ZFHX2; HIC1; EYA3; ZSCAN31; DOT1L; ZNF471; CHD2; ZNF780B; ZNF136; POU4F2; TFDP3; ZNF224; ZNF215; ZNF345; ZNF423; POU3F2; AIRE; VHL; ZNF124; SCRT1; SSX7; ZNF507; NFKBIB; CIITA; ZNF74; ZBTB44; POU3F4; SMARCA4; NEUROG3; ZNF549; SOX5; RORB; EMX1; KLF8; ZNF510; HOXB1; ZNF264; ZNF223; ETV2; ZNF273; NKX6-1; ACTL6B; ZNF234; NR6A1; APBB1; ALX4; BCL11A; ZNF80; ZFPM2; PRDM5; ETV3; GSC2; ZNF197; FEZF2; TAF1; NR1H4; TBR1; ASCL3; ZNF675; IKZF3; ZNF221; PAX1; ZNF674; ZNF235; FOXL1; ERBB4; ZSCAN16; ZNF391; ZNF81; ZNF550; POU4F3; BRDT; BRWD1; THRA; ZNF180; SPI1; NR5A2; HOXC5; FOXE3; LIN28A; TGIF2; POU2F3; ZNF248; ZNF208; HIPK2; ZNF695; ZBTB7C; FOXO4; DMRT1; ZKSCAN8; FOXB1; ZNF41; ZNF107; ZNF764; FHL5; TSHZ2; ZNF506; SRCAP; ASH1L; DLX4; POU5F1B; ZNF701; ZNF236; THAP9; TCEA2; NEUROG2; PRDM16; PPARA; HNF1A; HOXB8; LHX1; DCC; GFI1; CBX8; ZIC3; ZNF257; PAX4; ZNF835; ZKSCAN4; KMT2D; PAX7; ZNF682; LMO1; HNF1B; ST18; ZIM2; TULP2; POU3F3; NRL; PRDM14; FOXJ1; ATOH1; HOXA3; ZNF667; SALL2; ZNF93; ESRRB; EN2; SHOX; TULP1; ZBTB48; GBX2; ZNF696; ZNF430; ASCL2; MNAT1; CEBPE; ZNF778; FOXD3; MED31; TCF21; IKZF4; ZFP2; TCF4; CALCOCO1; PAX3; ZNF571; IRF8; ZNF253; PAX2; ZBTB39; SOX14; CEBPA; PRDM12; MAFK; ZNF75D; SIX5; TBL1Y; ONECUT2; ZNF155; SKIL; POU6F2; ZNF671; ZBTB7B; WHSC1L1; TBX5; FOXN1; ZNF493; ZKSCAN7; ZNF85; GCM1; MYCN; HES2; ZNF132; TUB; FOXH1; SRY; HEY2; RARG; TLX2; HIC2; ZNF142; ZNF768; SOX1; ZNF214; GABPB1; TEF; HOXA6; ZNF440; SPDEF; PRDM13; IKZF2; ZBTB3; NEUROD2; MYEF2; ZNF426; SNAI1; POU1F1; MNDA; PROP1; ZNF350; MEOX1; FOXL2; ZXDB; CBFA2T3; TAF4B; PAX8; ZNF35; ZNF205; TCF15; ZNF43; ZIC4; SNAPC4; NKX3-2; BAZ2A; SP1; ZSCAN9; EGR3; IRF6; SP140; ATF3; HEYL; E2F5; TLX1; TONSL; ARID5A; ZNF492; ZNF195; PAX6; THAP3; SALL1; NR2E1; RFX2; NEUROG1; HIF3A; WDR77; PRDM10; NKX2-8; CSDC2; NPAS1; DACH1; TBX4; ZNF254; ZNF606; GLI1; PAWR; CAMTA2; ALX3; INSM1; EGR4; VSX1; ATF7; ZNF117; SMARCA1; CREB3L2; NFATC4; POU2F1; NEUROD4; SKI; TBX1; KAT2B; NHLH1; NR4A1; EPAS1; NFE2; ZNF112; NEUROD6; ZNF239; ZNF177; GBX1; FOXC2; ZBTB6; ZNF623; SOX2; ZNF3; ZNF415; RELB; GTF2I; ING4; PGR; POU6F1; DLX6; HNF4G; ARID3B; NR1I3; REL; SP4; EVX1; TAF1C; RFXAP; LBX1; ZNF133; STAT2; SOX21; TBX10; IRF9; ZNF358; ZFP37; MBD4; FOXF1; MSL3; ZBED2; ZNF34; HDAC11; ZNF287; RERE; SAP18; OLIG2; EMX2; CBX2; ZNF556; LHX6; ISL1; ZNF442; RORC; ZNF646; TFAP2B; MED14; OVOL1; ID3; ZNF222; SMARCD3; ZNF91; HIVEP2; TAF6L; SIX6; FOXA1; MLLT10; ZNF135; KLF15; LHX3; NR4A2; KDM5C; ZNF394; NR4A3; GRHL2; MXI1; ZNF573; ZKSCAN1; ZBTB20; TRIM25; WT1; ZNF45; LEF1; ZFP30; LYL1; NKX2-5; TDRD3; CDIP1; ZNF14; RARB; CIR1; HOXD13; TBX21; CUX2; THAP7; ZNF529; PHOX2B; ZNF710; CIC; ZFY; ZNF480; BACH2; ZNF652; CNOT3; JUP; NEUROD1; TP73; MEIS1; ZNF611; CAMTA1; RING1; HOXD9; CD3D; CBL; PITX2; IRF5; MEOX2; CCNH; HOXB5; BARX2; HHEX; SOX11; SHOX2; ZNF467; BPTF; OVOL2; POU2F2; EHF; HOXA4; VGLL1; JUNB; MYCL; ATN1; ZNF551; GATA4; CBX7; ZNF557; ZNF552; ZNF334; TERF1; NKX2-2; GON4L; KAT6B; CALR; SMAD7; STAT4; ZNF331; ZFP69B; KLF13; CREG1; GFI1B; ZNF141; ZNF304; MDM4; TAL1; EP300; PRDM1; NR3C2; ZNF44; MZF1; BAZ2B; ZNF232; ZXDC; MEIS2; TEAD3; TFDP2; ZEB2; SSBP3; IRF1; NFATC1; NR0B1; ZNF219; ZNF184; RORA; ZNF226; MKL1; HABP4; ZNF10; MSX1; ING1; GATA6; MKL2; PEG3; ZNF516; BHLHE41; TRPS1; WWC1; TAF1A; NR1H3; CREBZF; ZNF22; ZNF544; ZNF354A; DLX2; PKNOX1; TULP3; ZNF8; HOXD11; NANOG; DBP; NFAT5; ZNF813; CRYM; SOX12; ZNF444; PRRX1; THAP10; SMARCB1; HOXC4; NLK; TGFB1; HLX; OSR2; PLAGL1; TRIM24; ARID3A; YBX2; SETDB1; FOXN3; ARID1A; KLF4; MYRF; ZNF419; DAXX; PHIP; STAT1; DLX5; BHLHE40; ZNF267; GATA1; AEBP1; HOXB6; POU4F1; ESRRG; ZNF32; SMARCC2; ZNF532; TLE2; PBX1; TDP2; ZNF665; E2F2; CERS6; CHD9; FOXE1; HEY1; HOXD3; RNF14; TFEB; ZNF165; KDM5A; CREM; BIRC2; CITED2; NFE2L3; GATA3; BNC2; ZNF83; MECOM; ZNF432; RBFOX2; PBX3; ZHX2; CHD7; NFATC3; ZMYM2; SPIB; SCAND1; ARNT2; INSR; ID4; TCF7; ZNF589; ZIC1; ZSCAN18; TLE4; HOXA10; IKZF1; LMCD1; TBX2; TOX3; MYB
Down-regulation 178 FOSL1; CDK7; CCNA2; FHL2; TCERG1; HNRNPD; ATF6; NUP62; RBM14; CENPF; NFIL3; TBL1X; SIX2; FOXD1; USP22; SUV39H1; BRD8; TSC22D3; BRCA1; EZH2; HMGB2; ZBTB16; RBBP4; HIF1A; SMAD3; MNT; MLX; NCOR2; SF1; VEZF1; BLM; CTBP1; CCDC59; AATF; SUZ12; DEK; KLF9; TAF9; CEBPB; PTTG1; NRIP1; NELFB; RAN; DNAJC2; CRK; BRD3; RHOA; NCOR1; SSRP1; IRF4; UBE2I; ZNF672; SAFB2; ADRB2; ATF1; NFKB1; ZNF263; BCL10; SNW1; C1D; CRY1; FOXJ3; HOXA5; BMI1; RBM39; RNF6; NFE2L1; GTF2IRD1; MLXIP; NCOA6; SIAH2; MED4; NCOA4; RELA; MBD2; TRIM29; NR2F2; SFPQ; BCLAF1; KAT8; ZBTB11; YWHAB; DDIT3; NONO; ZNF281; ZBTB7A; ENO1; FOXK2; NR2F6; KLF2; RARA; RRN3; CHD1; SOX10; RBPMS; PQBP1; SMARCE1; IRF2; MED6; TRIM32; AHR; CDK9; WHSC1; AFF1; ADNP; RBBP7; TGFB1I1; SAP30; TRIP6; HOXB7; KAT5; FOXO3; STAT3; ZNF217; SREBF1; KAT7; ING2; RNF10; ARNTL2; TSC22D2; TLE1; ZNF146; LOXL2; XRCC6; TEAD4; NFYB; TCFL5; PUF60; ATF5; JARID2; RREB1; HOXC6; PATZ1; MED1; TSC22D1; CBFB; KLF7; RNF4; TGIF1; KDM5D; CTNNB1; EYA2; NKX3-1; SOX9; CEBPG; ZNF266; RFC1; UBE2B; FLNA; ZFP36L1; ATF4; DDX5; PURA; BTG1; PITX1; CBX3; ZNF131; ZMYND8; CEBPZ; HOXC10; PIR; BRD4; NCOA3; JUND; MAGED1; FOXO1; SIX1; FOSL2; PPARG; KLF5; IFI16; SMAD1; TFAP2C; IKBKAP; SSBP2; ZBTB18; FOXC1; THAP11