Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11383	Canertinib	GSE70138	HME1	Human	24h	0.12uM	EID0014

Response Information :

Types	Number	Response transcription factors
Up-regulation	63	ISL1; TCEA2; TP53; JUP; CREG1; PBXIP1; ID3; TSC22D3; SOHLH2; MEIS2; OSR2; LYL1; NFKBIA; RFX5; ZNF423; PIR; ATF4; FOSB; STAT6; MECOM; FOXO3; MZF1; ERBB2; E2F8; HDAC9; PNRC1; FOXE1; RXRA; SOX17; TRIM22; FOXG1; LEF1; ID1; HOXA5; PAX6; RBFOX2; ARID5B; IRF1; ZIC1; SHOX2; TOB1; SOX11; FOSL2; BTG1; HMGN3; TWIST1; SCAND1; STAT1; ARID4B; NR0B1; PITX1; ZFPM2; RBPMS; INSR; MEOX2; KLF5; PBX1; HMG20B; IRF8; ESR1; ZSCAN18; EMX2; BHLHE41
Down-regulation	36	HMGA2; EGR1; GCFC2; TAF9; CENPB; ABL1; XBP1; NRIP1; CBFB; SUB1; SMAD2; RUNX3; YWHAB; BHLHE40; WWC1; SERTAD2; ENO1; TGFB1; RNF4; SNAI2; CBX3; NFAT5; SOX9; TBL1X; NPAS2; HOXD1; HMGA1; MNAT1; EGR3; TOX3; ETS2; MYB; HOXB6; ZBTB38; MYBL1; KDM5D