Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11374	Afatinib	GSE70138	HME1	Human	24h	10uM	EID0014

Response Information :

Types	Number	Response transcription factors
Up-regulation	86	PCBD1; HDAC6; DDIT3; FOXO4; ZNF222; HINFP; CALCOCO1; GTF2IRD1; CEBPG; PCGF1; HDAC5; ATF4; CIR1; TRIB3; PIR; KLF11; MXI1; PHF1; SP2; TSC22D3; SIRT7; AIP; ATF3; TRIP4; ZFP64; ZIC1; ZNF136; HTATIP2; ZNF44; SREBF2; MAF; SAP18; ZSCAN16; RORA; TAF5; KAT6B; HDAC9; ZNF426; LPIN2; SUPT7L; FOXN3; ISL1; EYA1; SETD2; TDP2; NCOA2; PHF20; ST18; RNF6; CREM; JUND; HOXC10; TP53; TGIF1; CREG1; ZNF232; NRBF2; CERS6; ZNF32; TAF11; TBL1X; PAX6; TULP4; MAFB; VGLL4; HMGN3; NFAT5; IRF9; REPIN1; BAZ2B; ZNF423; HEY1; STAT5A; CDK8; SPEN; DACH1; ELF5; EYA2; ZNF652; NR1D2; ERBB4; ZNF91; TCF7; ZSCAN18; LEF1; WT1
Down-regulation	84	MYCBP; CDK2; HES1; RUVBL1; TFDP1; HMGA2; EGR1; DNMT1; KMT5A; ZBED2; ILF2; SMAD3; HNRNPD; CCNA2; MYC; C1QBP; WWTR1; ELK3; ENO1; PSMC3; OLIG2; SMARCA1; WNT4; FLNA; TRIM28; POU2F2; ID3; ADRB2; TFEB; SUB1; SF1; CBFB; TGFB1I1; RUVBL2; CDK9; LOXL2; PTRF; PA2G4; ERG; TGFB1; ETS2; CALR; FOXL2; TCF4; HHEX; CHD9; ZMYND11; E2F8; HLF; NKX2-1; TRIM22; CREBZF; WWC1; ZBTB16; HOXB6; SFPQ; ZEB1; TFAP2C; PITX1; EHF; RBBP4; YAP1; HSBP1; BCLAF1; MBD2; BASP1; NRIP1; PURA; NR2F1; TBL1XR1; FUBP1; FOXF1; NKX2-2; UBE2I; PAX5; RBPMS; ZMIZ1; IFI16; TBX3; SOX9; POU2AF1; ID1; SSBP2; PBX1