Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11344 Palbociclib GSE70138 HME1 Human 24h 0.12uM EID0014
Types Number Response transcription factors
Up-regulation 45 DMTF1; CRYM; MNAT1; TSG101; SOX15; ZNF195; ZBED2; TBX3; PBXIP1; MXD1; HOXC6; CTR9; OSR2; BTG1; DEAF1; EGR4; PPARG; EGR1; RCOR1; TGIF1; ZNF165; TSC22D1; FOXL2; ARNTL; ARID4B; IRF6; TBL1XR1; BHLHE41; IRF7; HOXC4; ZMYM2; TFEC; IRX5; NR4A1; TRIM22; MYCL; TGFB1; DLX2; KLF6; FOXF1; MYRF; TXNIP; LOXL2; KLF10; DACH1
Down-regulation 58 CCNA2; CENPF; FOXM1; MYBL2; DEK; HMGB2; PTTG1; PBRM1; ING3; ZNF512B; WHSC1; ZNF281; WWC1; RXRA; LHX2; ELF5; NEUROD1; EDF1; SP110; ELF4; ZNF22; SMARCA2; ZNF331; HHEX; E2F8; PURA; NFIB; KLF9; SERTAD2; ATF4; NRIP1; ZNF232; SMARCA1; GTF3A; PBX1; NR2F2; EYA2; WWTR1; NR1D2; PSIP1; ZEB1; BACH2; CEBPD; PEG3; IFI16; ZFPM2; HOXB7; SOX11; MAFB; ZIC1; FOXC1; MYBL1; SATB1; THAP11; KDM5D; CREB1; NFATC3; ZNF586