Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11342	Palbociclib	GSE70138	HME1	Human	24h	1.11uM	EID0014

Response Information :

Types	Number	Response transcription factors
Up-regulation	89	SOX4; TRIM22; RELB; RFXANK; RFX5; HDAC9; NR1H2; CUX1; RSF1; HAND1; TSC22D1; FOSB; TDP2; ZBED2; MEIS1; MEIS2; ZNF264; IRF9; SND1; ZNF91; JAK2; SP110; HIVEP2; ZNF131; ZIC1; SOX17; ZNF133; STAT6; DMTF1; CREB3L2; MXI1; AES; IRF6; ZKSCAN1; TFEC; JUN; TRPS1; SP100; TRIP6; MLXIP; PEG3; ZNF331; CSDE1; POU2AF1; ZHX2; NFIC; BCL11A; CRYM; MAFF; ERBB2; ZNF93; NR4A3; PBXIP1; MYT1L; SALL2; HEY1; SCAND1; NCOA3; LITAF; WT1; TGFB1I1; TRIM29; NR4A2; BTG1; ID3; FOSL2; INSR; HLX; EGR3; RUNX1; MTA1; BNC2; ZNF652; RBFOX2; ESR1; ELF3; PBX3; HOXB2; COPS2; ZMIZ1; CREG1; MAGED1; LEF1; SOX9; SOX11; BHLHE41; ZFPM2; KDM5D; ARNT2
Down-regulation	62	CCNA2; CENPF; FOXM1; EZH2; MYBL2; HMGB2; WHSC1; PTTG1; ELF2; TFAM; SSRP1; BRCA1; ZNF227; SUV39H1; HMGB3; DEK; BRD8; ITGB3BP; E2F8; DNMT1; CCDC59; ING2; KLF11; CBFB; TOPORS; HSF2; CBX3; CARHSP1; NPM1; RNF4; MYBL1; SAP30; TEAD4; BLM; YEATS4; HOXC10; HMGB1; RAN; HOXC6; ATF1; RBBP7; VEZF1; HLTF; SFPQ; FOXD1; FUBP1; GTF3A; BCLAF1; NR1D2; TOB1; NFIB; HOXB7; MAFB; TXNIP; ADRB2; ZBTB18; RAD21; CEBPD; SMAD1; TWIST1; IRX5; THAP11