Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11340	Palbociclib	GSE70138	HME1	Human	24h	10uM	EID0014

Response Information :

Types	Number	Response transcription factors
Up-regulation	96	GMEB2; ZNF91; JUP; EBF2; PRDM12; TCEB2; ZNF3; PHF1; ZKSCAN1; GATA4; TAF1D; ZNF14; RFXANK; KLF13; LEF1; NR1H2; ZNF652; ZNF224; MEF2C; RING1; ZNF493; DLX2; RFX5; CEBPE; ZBTB43; ZNF430; MECOM; CDK9; PEG3; IRF9; SOX4; ZNF350; ZNF394; YEATS2; MAF; ZNF131; ELF1; ZFP36L1; MXD4; SP100; OSR2; BTG1; PLAG1; BRD2; HIC2; SMAD2; CSDE1; FOXA1; ZNF506; YAP1; ZNF239; FOXO3; GATA6; RUNX1; TCF12; SOX17; FOXO1; BACH2; ZIC1; FLNA; LPIN2; ZNF107; NFATC3; HIRA; MAFB; TFDP2; SCAND1; ZFHX4; ERBB2; ZNF467; NFATC1; REPIN1; SHOX2; CBFA2T3; CERS4; RBPJ; NFAT5; NANOG; CBX6; ZHX2; HLX; ESR1; MSX1; TXNIP; ZNF83; ZNF423; CD3D; MEOX2; TRIB3; MEIS1; ZMYM2; NKX3-1; TCF7; SOX9; SOX11; ARNT2
Down-regulation	85	CCNA2; CENPF; EZH2; PTTG1; FOXM1; SSRP1; CDK2; SAP130; DNMT1; PARP1; CBX5; BRCA1; SUV39H1; HMGB2; RBM14; BLM; HNRNPD; MYBL2; HES1; WHSC1; GMNN; NFIL3; SAP30; ITGB3BP; ARID1A; NUP62; MTDH; CITED1; C1D; SMAD1; TAF5; THAP10; DEK; YEATS4; TAF9B; CALR; NFYB; HMGB1; SF1; TOPORS; SFPQ; RUVBL2; TSC22D3; TFAM; RBPMS; BCLAF1; CITED2; PSMC3; CBX3; DNMT3B; MED21; HMGN3; NFIB; MEF2A; EHF; IRF2; RAD21; NR1H3; SMARCA2; PSIP1; SOX10; MYB; MYBL1; PRKDC; TRIM16; HMGB3; ZEB2; TLE4; EYA2; TBL1XR1; HMGA1; NPAS2; TOX; FOXD1; ELF5; HLTF; ZBTB18; HOXB7; TRIP6; ELF3; FOXC1; BASP1; BHLHE41; ID4; THAP11