Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11274 Geldanamycin GSE70138 HME1 Human 24h 0.04uM EID0013
Types Number Response transcription factors
Up-regulation 421 FOXO4; SETDB1; PCBD1; TLE4; ZSCAN18; CALCOCO1; DYRK1B; RARB; ZNF225; ZNF446; MAML1; HNF4G; ARNT; PBXIP1; KDM5B; SCAI; PAX8; ARID5B; ZKSCAN4; ZNF613; ZNF224; CIR1; PPARA; ZNF117; E2F8; HBP1; SRY; HOXA4; ZNF155; POU6F1; IKZF3; PRDM2; ZNF75D; POU2F3; RFX3; HOXB3; ATF7; ZNF391; ZNF345; ELF2; TBR1; GRHL2; MZF1; PRDM9; ZSCAN2; BAZ2B; ZNF500; ZNF444; WNT4; MSX2; ZNF780B; ZNF175; FOXI1; ASCL2; VHL; KLF8; TCF15; TCF4; DMRT1; ZNF304; ZHX2; ZNF80; GCM2; CBFA2T3; HMX1; TTF2; ANKRD1; MEF2D; HOXD9; ZNF197; PBX1; ALX3; ZNF157; ZNF214; ZNF362; TEAD3; IRF6; MYF5; ZNF460; BPTF; TBX10; ZNF85; FLI1; ZNF132; ARID1A; MXD1; ZNF354A; ZKSCAN8; EN1; ZNF81; CIITA; MYOG; TULP4; ZSCAN5A; CEBPD; ZNF407; ZNF549; GATA6; PAX4; KDM5C; CRYM; ZSCAN31; ZNF606; RSF1; ZNF74; ZNF350; PNRC1; ZNF768; ZNF682; ZNF234; ZNF223; ETV3; TBX5; GSC2; RAX; MYCL; CHD2; PHIP; HOXB1; NR1H4; ZFP2; HOXD3; SIRT2; ZNF571; ZNF141; ZKSCAN3; ZNF440; CBFA2T2; ZNF665; ZNF174; ZBTB44; GLI1; MAML3; NEUROG2; SUPT7L; HOXD1; CBX7; HOXA2; FOXN3; SALL2; HIF3A; SOHLH2; ZFP69B; ZNF674; ZNF573; FOXL2; HMGN3; ZNF695; CDIP1; AFF3; CSDC2; POU6F2; ZNF235; EPAS1; OSR2; SSX7; TBX4; ZNF544; MEIS2; RBPJL; SOX18; ZNF112; PHF1; ARID3A; ZNF45; AR; ZNF507; ZNF276; SOX3; NFATC4; RING1; ZNF749; SNAI1; POLR3C; TCEA2; ZNF550; HDAC5; CIC; ERBB4; GCM1; ZNF394; SCRT1; PGR; TP73; ATOH1; TULP1; ZNF493; NR2F1; ZNF154; FOXE3; ZNF814; SUPT5H; ZNF91; TFAP4; ZNF12; ARID4B; BNC2; EMX1; ZNF133; PDLIM1; ZNF227; NFKB2; LZTR1; POU1F1; TRPS1; ZNF264; SETD2; TFCP2; RERE; ZNF205; EZH1; POU2F1; TFAP2C; ZNF33B; STAT2; SIX6; BCL11A; ARID4A; ZIC3; TLX3; ZNF254; ZNF701; PIAS4; SSBP3; NFATC3; ELF4; MED14; AFF2; ZFPM2; ZNF467; SIM1; DLX5; CNOT6; IRF9; SMAD4; ZNF419; ZNF358; WWC1; BRD4; CNOT2; NHLH1; ZNF222; SP140L; NR0B2; SOX12; TCF21; SPIB; ST18; NHLH2; PAX6; APBB1; SP4; THRB; HMBOX1; FEZF2; USP21; WT1; PRDM10; ZNF83; TSHZ2; SP1; CRX; SUPT6H; ZNF257; ZNF232; ZNF415; ZNF135; ZNF813; ZNF44; SOX17; HIPK1; FOXJ1; ZNF529; ZNF512B; ZNF43; ZNF671; HOXA5; GLI2; SP2; ZNF574; STAT6; PFDN5; TCF25; ZNF324; MED23; KLF3; HINFP; ZNF273; SOX2; SP100; ZNF219; EN2; ZNF423; ZNF211; ARID3B; RCOR1; PRDM14; NCOA1; DBP; EHF; ARHGAP35; MEOX2; BARX1; TULP3; MNDA; ISL1; PBX2; TXNIP; NAB2; MECP2; MED25; ING4; LDB1; ZNF131; ZNF331; EHMT2; TRAK1; TBX1; MEF2C; ZNF180; BNC1; CITED2; RREB1; ZNF217; EMX2; ZNF611; EYA1; PROP1; FOXE1; GATA4; MDM4; ELF3; TFAP2A; NCOA2; TAL1; TAF11; CXXC1; ARNT2; ZNF711; ERBB2; SIX3; MDM2; TRIM22; SPDEF; BRD8; SHOX2; TRIB3; NFAT5; ZEB1; PPP1R13L; ZMIZ1; NCOA3; FOXF2; SOX11; NFIC; UBE2B; MITF; ZNF266; LHX3; TOX; ZNF24; TGIF2; JUP; TCF7L1; ZNF268; ZNF165; SIM2; AFF1; MXI1; TCF7L2; MEOX1; HEY2; MEIS1; NR5A2; SUB1; TAF7; KLF5; TFEC; IRF7; ZNF580; POU2AF1; KAT6B; SMARCA2; E2F5; MYRF; KLF11; ESR1; FOSL2; CUX1; SOX13; TWIST1; CERS4; ELF5; AEBP1; MYBL1; ZEB2; PEG3; VPS72; PCGF2; HOXD11; BACH2; RBPMS; ID4; ASCL1; SIX2; TRIM16; TOB1; NR4A1; TGIF1; ZNF22; FOXO1; HLX; MAF; INSR; MLXIP; HEY1; HOXB2; RUNX3; MYB; HMG20B; THAP11
Down-regulation 92 FOSL1; HMGA2; MYC; NFKBIA; SUV39H1; RUVBL1; CCNA2; ELK3; PPRC1; IKBKAP; PA2G4; EDF1; TFDP1; GTF2A2; TSC22D3; SNAI2; BATF3; CBFB; NFIL3; DRAP1; MYCBP; MLX; ENO1; NUP62; PUF60; SSRP1; C1QBP; DR1; EZH2; XBP1; ITGB3BP; EGR3; EGR1; TCFL5; HNRNPD; RHOA; RAN; MED27; KLF6; BAZ1B; NELFB; RBM14; TSC22D2; NFKB1; NRIP1; ATF1; SFPQ; NFX1; DNAJC2; EED; JUN; TAF1D; JUNB; ARNTL; KDM5D; BMI1; TAF9; BHLHE41; DDX5; RNF14; HSBP1; ING3; TRIM32; NKX3-1; XRCC6; PPARG; YWHAB; GTF3A; ZBTB38; CNBP; KLF10; BHLHE40; RBBP4; JARID2; EGR2; MAFB; KLF2; BRCA1; SATB2; ETS2; MNAT1; CEBPB; KLF4; PITX1; ZBTB20; SAP30; NR2F6; FOXC1; BASP1; ID3; ZBTB18; ID1