Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11269 Geldanamycin GSE70138 HME1 Human 24h 10uM EID0013
Types Number Response transcription factors
Up-regulation 325 FOXO4; PCBD1; CALCOCO1; OSR2; MYOG; SIRT2; PRDM2; ZNF506; ZBTB7A; ZSCAN31; SOX12; CSDC2; TCF15; CBFA2T2; TEAD3; ZNF426; RAX; GRHL2; L3MBTL1; PAX8; CRTC1; ZNF500; SCAI; ZNF224; SREBF2; ZNF91; TLX1; MZF1; CITED2; MED13; ARID5B; HMX1; ATN1; TBX5; SIX5; ZNF175; PRRX2; ZNF76; HBP1; ZNF446; KDM5C; PBXIP1; PIR; BNC2; IKZF4; PIAS1; KDM5B; ERBB4; HINFP; E2F8; SUPT7L; ZNF778; HOXD3; HOXB1; EVX1; ING4; EZH1; APBB1; FOXL2; ESRRB; HIPK1; ZKSCAN4; SETDB1; ETV2; NFKB2; RNF2; ARNT; MEIS2; PHF1; TLX3; GLI1; TRPS1; TRIP11; CDX4; ZNF292; MED12; PITX3; ZNF573; TBX4; ALX3; ZNF304; ZNF74; ZNF253; THAP3; ELF4; ATOH1; ZNF205; GBX1; LHX1; RING1; ONECUT2; PDX1; ZNF174; ZNF345; NFAT5; SOX2; ZNF576; PHIP; ZNF75D; ZNF79; ZNF688; E2F6; TULP1; TULP4; HOXA4; MGA; NPAS1; ZBTB44; ZBTB7B; CBX7; ZNF135; PKNOX2; TP53; ZFX; PIAS4; HOXA3; ZNF665; SOX18; ZNF250; SSBP2; ZNF225; KAT2B; HIF3A; CUX1; YEATS2; ZNF646; HAND2; TBX10; GLI3; ZNF415; ZNF771; ZNF93; ETV7; ZFHX2; GATA6; CIR1; HEYL; KLF15; RBBP5; GBX2; TCF21; RARG; NCOA2; CREG1; CDIP1; ATF7IP; IRF7; CERS4; EMX1; TSHZ2; ZKSCAN1; HOXA7; ZNF423; HIC2; ZNF16; BARX1; KLF1; DLX4; GLI2; ZNF12; ZNF248; RARB; CRX; ZNF177; ZNF362; CTBP2; VENTX; TULP3; THRB; ARID3A; TTF2; RXRG; TCF20; ZNF444; JAK2; ZNF337; ZNF623; CEBPD; ZNF133; TOB1; SUPT4H1; TSC22D4; ZSCAN9; ZNF154; MYF5; TP73; ZNF544; TBX3; PBX1; IRF6; ZHX2; HOXA5; ZNF124; CEBPE; ZNF232; GFI1B; ARHGAP35; GATA4; PBX3; UBE2B; LDB1; RBM39; ZNF33B; CRYM; BCL11A; ZNF83; PRDM12; SMARCD3; SMAD6; PNRC1; MECP2; NHLH1; KDM2A; ZNF611; MYCN; ZNF117; ZNF324; ZNF711; ZNF219; CBFA2T3; SOX4; WNT4; SIX3; ZSCAN18; ZNF467; GATA1; EP300; PEG3; ZNF112; ZNF264; TFAP2A; ZSCAN16; ZNF667; BAZ2B; NCOA1; KMT2A; RXRA; CHD1; MED25; EMX2; IRF9; RSF1; NFE2L1; SP2; STAT6; HOXD1; NFE2; ZNF44; NPAS2; ARID1A; PAX6; VGLL1; ZNF671; PROP1; HMBOX1; SOX13; SHOX2; ZNF239; NR2C1; SALL2; FOXE1; NHLH2; PEX14; NFATC4; ZNF148; KLF4; LYL1; MEOX2; MEIS1; ZNF532; TFDP2; IRF1; HOXB13; ZNF7; CREBL2; TFAP2C; TRIM16; ZNF652; ZEB1; NFATC3; AR; ZFHX3; NANOG; MAF; MNDA; PITX2; ARNT2; FOXF2; ZMYM2; ZMYND8; TP63; DLX5; WT1; INSR; MXI1; EN1; MNAT1; ZNF331; BRD4; RBFOX2; YAP1; ESR1; KLF11; ZNF512B; TCF7L2; SOX17; ZBTB20; RYBP; ERBB2; CD3D; MYCL; VPS72; ZFPM2; RBPMS; TRIM22; TRIB3; TOX; MECOM; JUP; ZNF589; CREB1; AEBP1; ASCL1; TLE1; THAP11
Down-regulation 102 PDLIM1; FOSL1; HMGA2; MYC; SSRP1; SUV39H1; RUVBL1; CCNA2; PA2G4; TFDP1; CBFB; HES1; TSC22D3; ELK3; YBX1; PTTG1; NFIL3; HNRNPD; ITGB3BP; PPRC1; DRAP1; MYCBP; SMAD2; RUVBL2; URI1; BRCA1; C1QBP; IKBKAP; EZH2; EGR3; XBP1; TRIM28; RAN; RHOA; KLF9; CENPF; PRKDC; C1D; HMG20B; VGLL4; RNF4; SFPQ; MBD2; HLTF; NPM1; SNAI2; BCL10; TCFL5; TRIM32; RBM14; NCOR2; RNF138; LOXL2; BMI1; EGR1; BHLHE41; ETV1; SSX1; MYBL2; EGR2; NEDD8; NUP62; CDC5L; FOXM1; RBBP8; APEX1; HMGA1; RNF14; NFKB1; HMGB2; KDM5D; ZBTB16; NCOA4; SMAD7; FOXD1; FLNA; TGFB1; BCLAF1; UBE2I; JARID2; CHD7; ENO1; CEBPZ; HOXB7; DEK; PAX5; NRIP1; JUN; LEF1; TCEA1; HOXB6; MSX1; KLF10; TXNIP; SMAD1; PPARG; BHLHE40; DMTF1; ID3; SATB2; ID1; HOXC6