Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11218 Gsk-2126458 GSE70138 HME1 Human 24h 1.11uM EID0013
Types Number Response transcription factors
Up-regulation 140 SOX4; TSC22D3; FOXO4; HBP1; ZNF506; CALCOCO1; CDK7; GRHL2; ZNF76; EZH1; RELB; ZBTB43; VGLL4; ATF4; NFKBIA; HDAC5; BTG1; ING4; IRF6; MXI1; ZNF33B; MAF; FOXJ3; CSDC2; SCAI; FOXO3; HIVEP2; SETDB1; CBFA2T2; NR2C1; ZNF358; UBE2B; PRDM4; SSBP3; SRCAP; NCOA2; ZXDC; ZMIZ2; ZNF224; MED12; BRD8; CBX7; CIR1; PBXIP1; ZNF688; EP300; KAT2A; CREBL2; ZBED1; HOXB13; OSR2; ZNF83; PAWR; ZHX2; COPS2; PRDM2; ZZZ3; BPTF; ZNF32; PFDN5; TCEA1; BACH2; INSR; FOXN3; KLF4; PNRC1; ZNF623; TCF7; ZNF24; VDR; ZNF419; ZNF768; MED23; ARID5B; PLAG1; ZIC1; RBPJ; NFIL3; TCF12; CREG1; ZNF44; AES; BAZ2B; ZNF354A; ZNF606; ZNF219; LDB1; ETV1; KLF7; CNBP; CERS4; HMBOX1; RAD21; SOX10; KLF5; BCL11A; CBFA2T3; ZBTB16; RORA; CERS6; KAT6B; TP63; ZNF160; ERBB2; TGIF1; ZNF264; IRX4; PPARGC1A; ELF3; SALL2; APEX1; CTBP2; KLF11; NR4A2; ZFP36L2; SMAD6; ELF5; KLF6; CITED2; ZMYM2; ARNT2; HDAC9; ZNF331; TXNIP; EMX2; FOXO1; FOSB; ZNF91; HOXD1; AEBP1; AFF1; ATF3; TBX3; HEY1; TLE1; BRD4; DACH1; BHLHE41; GATA2; THAP11
Down-regulation 69 MYCBP; CCNA2; SUV39H1; TFDP1; RUVBL1; PARP1; FOSL1; EZH2; GTF2A2; DNMT1; SFMBT1; DRAP1; PPRC1; MYBL2; PTRF; WDHD1; WDR77; RBM14; PA2G4; CHAF1B; RUVBL2; EGR1; CBFB; ITGB3BP; PTTG1; XBP1; EGR4; TFAM; GATAD2A; BHLHE40; PREB; NUP62; C1QBP; ENO1; HNRNPD; PITX1; ZNF200; GABPB1; EED; CCNE1; BRCA1; LOXL2; CENPF; TSC22D2; MYBL1; DNAJC2; TEAD1; SFPQ; MED17; PSMC3; ILF2; RAN; BAZ1A; CALR; HMGB1; SUB1; ATF5; KLF10; YWHAB; NRIP1; ZEB1; FLNA; HOXB6; FOXF1; TRIM16; SAP30; SMARCA1; SOX9; MEIS2