Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11208 Hg-6-64-01 GSE70138 HME1 Human 24h 0.12uM EID0013
Types Number Response transcription factors
Up-regulation 63 TSC22D3; MXI1; ATF4; ATF3; CALCOCO1; HES1; ZBED1; EZH1; ZBTB16; TXNIP; ZNF589; UBE2B; CEBPG; STAT5A; NR0B1; TRIB3; CBX7; ZNF419; NFIL3; PLAGL1; DDIT3; MAFF; SP100; NFE2L1; PRRX1; ZNF32; EGR3; CREG1; NCOA2; EGR2; MITF; SIM2; SOX10; MAFB; TOB1; RORA; JUNB; CITED2; ZEB2; ZNF117; FOXG1; PHF20; CREBL2; LPIN2; MAF; NEUROD1; TCEA1; PURA; HLF; KLF11; TFEC; ERBB2; KLF2; FOXO1; ZBTB18; BTG1; INSR; ST18; THAP11; ID4; KDM5D; HOXC6; TLE1
Down-regulation 54 CCNA2; RUVBL2; MYCBP; EZH2; SUV39H1; FOXM1; WHSC1; CENPF; MYBL2; SSRP1; HMGB3; IRF2; NFKB1; E2F8; RBM14; ARID1A; POLR2A; TAF5; SMARCA1; DBP; HNRNPD; CHD4; CALR; RBBP8; ZMIZ1; PAXBP1; CNOT3; PTTG1; TRIM29; NR2F6; WNT4; LEF1; ID3; BCL3; ILF2; POU4F1; HHEX; SREBF1; PBX2; SMAD3; ZFHX3; TCF4; BRCA1; RBFOX2; SMARCD3; NKX3-1; RYBP; SMAD1; SOX2; ID1; MECOM; PEG3; SIX2; MEIS2