Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11202 Azd-7762 GSE70138 HME1 Human 24h 1.11uM EID0013
Types Number Response transcription factors
Up-regulation 58 E2F2; FOXO4; CEBPD; NFKBIA; MNAT1; MAK; WNT4; LHX1; TCF15; MNX1; SIX1; CIR1; HOXD3; TBX1; HMGN3; ATOH1; WT1; MXI1; BTG1; HOXB13; TLE4; SALL1; NCOA3; NR3C2; CUX2; DMTF1; HIPK1; MNDA; ZNF467; CTBP2; TCF21; NFE2L3; NR4A2; PLAGL1; MEOX1; MEOX2; SIM2; TBX3; SOX11; SALL2; EMX2; HOXD1; ZFPM2; MYCL; FOXO1; ZBTB20; PCGF2; OSR2; CITED2; HOXA5; ERBB4; HMG20B; MYB; MEIS2; HOXC6; DACH1; JUP; THAP11
Down-regulation 18 FOSL1; HMGA2; XBP1; DNMT3B; BHLHE40; BMI1; KLF10; RBBP4; FOXC1; HDAC9; TRIM16; VPS72; HEY1; SMARCA1; HMGA1; ID1; TOX; SOX9