Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11192 Azd-5438 GSE70138 HME1 Human 24h 0.04uM EID0013
Types Number Response transcription factors
Up-regulation 45 GATA3; BATF3; SSX1; PPARG; KDM2A; ITGB3BP; ATF3; PIAS2; MSC; HAND1; HOXD10; HOXA10; PHOX2B; RBPJ; ZNF589; NFYB; HDAC1; NR2C1; TOB1; HTATIP2; IRX5; NR1H3; ZNF721; TP63; MDM2; NCOA1; PIR; HOXA11; ZNF266; KLF9; TBX2; BCL11B; TCF7; SATB1; TGIF1; MKL2; EYA2; KDM5D; NRIP1; STAT3; ZNF160; ZNF91; TSC22D1; BASP1; DACH1
Down-regulation 73 HDAC9; SMARCA1; SP3; UBE2L3; TERF2; ZBTB11; HHEX; VDR; ZHX2; NR4A2; SP110; CLOCK; IRF8; IRF2; ST18; PEG3; CNOT6; GATA6; POU4F1; RREB1; SOX17; NAB1; ARNT2; SALL2; BAZ2B; FOXN3; E2F5; MEIS1; ZNF232; PBXIP1; EHF; PPP1R13L; NCOA2; CEBPB; TCF7L1; APEX1; DLX2; MSX1; YAP1; TRIM22; MEIS2; FOXO1; TRIM29; TGFB1; CTBP2; TULP3; HOXB6; SOX9; TFAP2C; ZFPM2; JUND; WT1; NFIB; MAF; KAT2B; ZIC1; ZNF165; HOXD1; NR1H2; BACH2; HOXB2; TBL1X; PBX1; VPS72; IRF9; FOXC1; TXNIP; JUP; ASCL1; ESR1; CITED2; HOXC6; THAP11