Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11177 Bms-387032 GSE70138 HME1 Human 24h 0.37uM EID0013
Types Number Response transcription factors
Up-regulation 590 EGR1; NR4A2; RFX1; ATF3; ZNF506; CARF; MAK; ESR2; SCAI; L3MBTL1; NR4A3; ZNF136; ZNF85; ZNF816; NFIX; HMGXB3; ZNF91; THRB; IKZF2; ZNF221; CCNH; ESR1; BIRC2; ZNF770; GBX1; HOXB1; PDX1; NR4A1; PPARA; TAF5L; HOXC5; POU3F2; REL; SRY; HNF4G; NR2E1; ZNF701; ZNF331; ETV3; SSX7; ZSCAN2; ZFPM2; ZFP2; ZNF253; RING1; HDAC9; ZNF154; ZNF345; TCF7; VENTX; ZIC4; LIN28A; NR5A1; MED31; CBL; FOXJ1; SOX17; HIVEP3; FOXH1; ZNF415; ZNF696; ONECUT1; EHMT2; ZIM2; LHX1; SSX3; GLI2; ATF7; ASCL2; ZNF75D; MEF2C; PRDM9; ZNF549; ZNF550; ZNF264; SOX3; TSHZ2; ZNF208; ZNF440; HNF4A; SNAI1; RORC; PHF1; MAML3; HOXA2; TTF2; ZNF76; ZNF391; RAX; RFX3; PAX1; NEUROD6; HDAC11; ZBTB3; FOXL1; ZNF835; NR1I3; NR6A1; FOXD3; IRF6; ESRRB; TBR1; CD3D; IKZF3; HES2; ETS1; ALX4; ZNF507; NKX2-5; ZNF682; NFATC4; ZNF556; WT1; SOX1; MYBBP1A; FOXE3; ZNF675; ZNF215; KMT2D; ZNF225; EMX1; MXI1; ZSCAN31; ZNF611; CHD2; RBPJL; ZKSCAN3; TFDP3; LBX1; NKRF; ZNF671; CBX7; BCL11A; MLLT1; ZNF778; HESX1; ZNF195; ATOH1; ZNF117; TEF; SOX18; SPI1; IRF8; NACA2; TBX5; HIRA; ZSCAN9; PRDM5; ZBTB44; SCRT1; AFF2; SHOX2; TULP1; AFF3; HOXD12; ZNF93; ZNF43; FOS; TLX1; ERBB4; NFKB2; ZNF205; TULP2; CREM; MECP2; ZNF493; FOXL2; ZNF239; VHL; CBFA2T3; POU6F1; GCM1; ONECUT2; DCC; GRHL2; ZNF780B; SIX6; LHX3; HNF1A; PRDM2; SOX14; HOXC8; ZNF362; PRDM14; JUN; ZNF667; DOT1L; PROP1; NEUROG2; POU6F2; ZNF665; ZNF544; NR1H4; POU3F4; ZNF814; ZNF74; NEUROD4; E2F4; OVOL1; ZNF471; GCM2; MDM2; ZNF224; NEUROG1; ZNF407; CIITA; ZNF606; FEZF2; NHLH1; POU4F3; PRDM10; CDX2; ZNF257; GATA3; ZXDC; ASCL3; CAMTA2; HIC1; CDX4; TAF1; LDB1; ZNF81; BRDT; WHSC1L1; GSC2; NPAS1; ALX3; ZNF749; HOXA3; HHEX; TUB; MAFK; CAMTA1; ARID5A; ZNF254; ZXDB; E2F2; ZNF235; HIVEP1; CRX; BRWD1; SPIB; ZNF141; HOXA6; HAND2; HMGA2; ZNF223; ZKSCAN4; PAX3; TBX4; ELF4; KLF15; LHX6; NEUROG3; PAX4; MSX2; ZNF107; PRDM12; ZNF571; GRIP1; CBX2; ZNF83; ZNF157; ZNF350; MEF2D; KAT2B; ZNF44; GLI1; ZNF674; RNF2; SIX5; HDAC5; ZNF695; PAX7; CERS6; THAP9; TONSL; MNX1; HOXD13; TCF21; ZNF10; ZNF394; ZNF155; KLF1; NR0B2; FOXB1; TAF1C; ZSCAN18; ZNF124; ZNF304; PBXIP1; PITX3; SRCAP; POU1F1; HOXB8; ZFHX2; ZBTB7B; ZNF711; TP73; VSX1; TBX21; ETV2; DLX6; AIRE; DLX2; NKX6-1; ZNF132; DBP; MAFF; UTF1; HEY2; PCBD1; ZNF573; ZKSCAN8; MYCN; CRTC1; SOX2; ZNF80; PRDM16; CEBPE; ING4; PRDM1; STAT2; DLX4; EVX1; RSF1; KDM4C; HOXB5; ZNF180; SOX21; RXRG; AR; IRF1; NEUROD2; SSX1; ELK4; ZBED2; ZNF623; LZTR1; ZNF287; ZNF214; HMX1; BARX1; ZNF250; BACH2; HEYL; WNT4; ZNF467; TAF4B; ZIC3; MED25; TFEC; POU4F2; ASH1L; POU5F1B; ZNF423; EGR3; HIF3A; GBX2; NANOG; ZNF8; NFATC3; ZNF135; CDIP1; RARG; HIC2; CIR1; CUX2; ZNF14; ZBTB43; MYEF2; ACTL6B; WDR77; GMEB2; POU2F2; ZNF646; TAF6L; ZNF536; ANKRD1; SKIL; ZNF557; GFI1B; DMRT1; OSR2; PKNOX2; ZNF184; ZSCAN16; SALL2; NHLH2; PEG3; E2F5; ZNF334; KDM5B; CCNT1; MDM4; FOXC2; HOXA4; ZNF787; HBP1; SNAPC4; ZFP37; ATN1; NFE2L3; STAT4; JUNB; OLIG2; SHOX; POU2F3; THRA; NR5A2; RARB; DLX5; ZNF771; LYL1; TRIM24; HINFP; HIPK2; ZNF669; ARID3A; PAX8; TGFB1; HSF4; CDX1; TBX19; MYF5; ETV7; CREG1; ZHX2; SOHLH2; HNF1B; TLX3; FOSB; HOXD1; HAND1; ZNF131; ZNF358; NAB2; EP300; MYOG; TGIF2; RELB; CALCOCO1; CSDC2; ZNF652; GATA1; TCEA2; SP4; GATA6; NKX3-2; MKL1; ZNF468; IRF9; SKI; ZNF710; TFAP2A; SUPT4H1; ZNF551; MYT1; ZNF33B; ZNF444; PRRX1; CBFA2T2; ZNF273; LEF1; PRDM13; HSF1; NFE2; APBB1; TCF15; NFATC1; THAP7; PFDN5; ZNF219; NOCT; ZNF133; ZNF500; ARRB1; MED12; NRL; PAWR; IRF5; ZNF492; HIPK1; ZNF516; ARID5B; KLF13; SATB2; MAFG; HOXD3; ZNF268; SUPT6H; EGR4; HOXB13; MED17; TFDP2; ZNF222; SP2; EHF; SPDEF; ZNF562; ZNF587; BHLHE40; ZFP69B; HEY1; ZNF202; ID3; ARID3B; ZNF586; EGR2; BNC1; WWP1; CNOT3; ARNT2; SP140L; ARHGAP35; CRYM; MEOX2; ZNF419; CNBP; NFE2L2; EMX2; SP140; TCF7L2; SUPT3H; TRPS1; FOXF2; ST18; NFAT5; VPS72; TRIB3; HLF; MYRF; TEAD3; CERS4; NCOA2; ZNF354A; GFI1; CEBPA; ZFHX4; CSDE1; SOX5; VGLL1; PAX5; KLF11; BNC2; INSR; MSX1; RUNX3; TERF1; PNRC1; BRD4; WWC1; ZNF654; TXNIP; NR2F1; CREBL2; PBX2; YAP1; PBX3; TAL1; FOXF1; MYBL1; SIX3; AEBP1; HOXB6; SMAD7; FOXA2; NR1H2; POU2AF1; ZNF274; RBBP8; ZNF160; DACH1; MYCL; NR3C1; TSC22D1; MEIS2; ZFP36L1; INSM1; HOXB2; TGIF1; MNDA; BHLHE41; ID2; ZNF589; ID4; TOX; IKZF1; MEIS1; GATA2
Down-regulation 158 CCNA2; SUV39H1; EZH2; NUP62; USP22; CRK; RBM14; CENPF; XBP1; ZMIZ1; TSC22D3; NFIL3; BRD3; SNW1; ATF6; NELFB; HNRNPD; BAZ1B; TRIM32; NFKBIA; MED1; CBX3; TBP; HMGB1; ADRB2; TRIM29; SSRP1; FOSL1; MLX; FOXM1; CDK7; ZNF189; BCLAF1; CENPB; ECD; HMGB2; EDF1; ZNF146; RCOR1; SOX4; TCF12; BLM; PREB; UBE2I; DEK; SMARCE1; BMI1; RBBP4; BTG1; BRCA1; SFPQ; ATF1; KAT6A; CNOT1; KAT7; ASH2L; CEBPG; TRIM28; RBPJ; TRIM16; CHAF1B; NCOA4; IKBKAP; WHSC1; SP3; MTDH; EED; PTRF; MED6; ZBTB11; NKX3-1; NRBF2; ZNF282; PTTG1; SAP30; TRIP6; RNF4; MED20; NCOA6; RUVBL2; RBPMS; BRD8; HMG20A; APEX1; CHD9; HOXA5; SMAD1; CBX5; NFYB; KDM5D; NAB1; PATZ1; NONO; ZBED4; MED4; NFIB; TBPL1; ADNP; DNAJC1; AATF; DDX5; NFE2L1; PUF60; CDK8; SMARCA5; ORC2; CBFB; RAN; NPM1; CRY1; CTR9; RNF111; ENO1; HOXC6; PRKDC; BASP1; AFF1; JARID2; ARID4B; TBL1XR1; ZNF12; NCOR2; MBD2; UBP1; ELF1; SIX2; DNMT3B; HOXB7; MAGED1; FOSL2; ILF2; GTF2IRD1; ZNF266; PCGF2; PURA; MNAT1; STAT3; BAZ1A; SNAI2; NRIP1; TLE4; ETS2; HMGB3; ZMYM2; MED24; CARM1; TSC22D2; ZBTB16; NR2F2; CEBPZ; NR2F6; TBL1X; TP63; SCAND1; FOXD1; ZBTB38; TLE1; SOX9