Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11172 Canertinib GSE70138 HME1 Human 24h 1.11uM EID0013
Types Number Response transcription factors
Up-regulation 73 NFKBIA; CEBPD; FOXO4; CREG1; TP53; TSC22D3; PCBD1; MED1; FOXO3; IRF1; CALCOCO1; TBPL1; MXI1; ATF3; TWIST1; DDIT3; HOXA5; PIR; ZNF358; PBXIP1; STAT5A; BTG1; DBP; AES; FLNA; LIN28A; SALL1; RXRA; TCEA2; MTA1; EYA1; EHMT2; FOSL2; TRIM22; ZNF266; ATN1; IRF7; NR1H2; PCGF2; PBX1; KAT6B; TRIM29; FOXG1; EYA2; PITX1; PNRC1; JUND; ZMIZ1; SALL2; SLC2A4RG; ISL1; MEIS2; CITED2; CALR; TGIF1; PLAGL1; ZNF264; NR1D2; JUP; SOX17; EMX2; ZNF331; RYBP; ZNF91; SIX2; ESR1; ZBTB20; SCAND1; MEIS1; ERBB4; HMG20B; SATB1; TLE1
Down-regulation 26 CRK; HMGA2; C1QBP; CCNA2; EGR1; FOSL1; ELK3; HES1; ARNTL2; SOX4; SFPQ; RAN; SSX1; YWHAB; TAF9B; BHLHE40; NPAS2; BMI1; NRIP1; TOX3; ZBED2; POU2AF1; BASP1; ID1; THAP11; TBX2