Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11167 Afatinib GSE70138 HME1 Human 24h 0.37uM EID0013
Types Number Response transcription factors
Up-regulation 63 CSDC2; TLE4; TSC22D3; CEBPD; ZSCAN31; EPAS1; TULP4; TRIM16; PHF1; BCL6; BACH2; KLF4; CTBP2; CTBP1; TRIM29; MED1; IRF6; HIRA; PPP1R13L; PLAGL1; ZNF665; TXNIP; ZBTB38; BAZ2B; ZSCAN18; E2F5; ADRB2; INSM1; ZNF721; BCL11A; BRD2; NR1D2; TOX; MTF2; HMGB3; RYBP; TCF4; CBFA2T3; ZNF264; KLF5; PCGF2; ZBTB20; ERBB2; IRF9; PAX6; BTG1; ATF3; TRPS1; ZNF91; MAF; DACH1; ID3; TRIM22; EMX2; FOXC1; PBX1; MEIS1; PEG3; AEBP1; TLE1; MAFB; BASP1; SATB1
Down-regulation 20 HMGA2; EGR1; WDR77; EGR3; CD3D; CREG1; CBX3; ELK3; ETV1; YAP1; PRRX1; MEOX1; ARID1A; PSIP1; RORA; EGR2; MKL2; KDM5D; BHLHE40; IFI16