Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11165 Afatinib GSE70138 HME1 Human 24h 3.33uM EID0013
Types Number Response transcription factors
Up-regulation 34 RELB; NFKBIA; CEBPD; TSC22D3; IKZF1; CREG1; TRIM29; TP53; ARID5B; HOXC10; BCL3; MYCN; PBXIP1; TRIM16; TLE4; ZSCAN18; DNMT3B; HSBP1; ZMYM2; TWIST1; FOXN3; ERBB2; BTG1; TCF4; HOXC6; KLF4; TGIF1; PHF20; ZFP36L2; ID3; ZBTB38; BASP1; TLE1; THAP11
Down-regulation 23 EGR1; WDR77; MED27; MECOM; TOPORS; NR4A2; BHLHE40; HSF2; ABL1; EGR3; IRF8; ARID1A; POU2AF1; ELK3; HMGA1; SMAD7; EGR2; NRIP1; ETV5; BHLHE41; IFI16; MEIS2; KDM5D