Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11131 Osi-027 GSE70138 HME1 Human 24h 0.04uM EID0013
Types Number Response transcription factors
Up-regulation 65 PAX8; PTRF; ZSCAN18; TXNIP; WWC1; SMARCC1; TCF4; EGR2; ELK3; POU5F1B; KLF6; MXD1; ID1; KLF4; ID4; SOX17; SMARCE1; CARHSP1; CTBP2; LHX6; EMX2; RERE; TFDP2; FOXE1; MYCN; GATA2; MITF; ZNF83; PHOX2B; HEY2; TRAK1; EGR1; MEOX1; PURA; ZNF665; DLX5; ESR1; ERBB2; ZNF117; NFE2L3; TP53; CTNNB1; TSC22D1; PEG3; PHIP; ZBED2; HHEX; IRF6; ZEB2; BHLHE41; MSX1; ZBTB20; HDAC9; MTA1; ZEB1; TBX3; FOSB; KDM5D; MAF; ASCL1; PBX1; BASP1; THAP11; TLE1; HOXC6
Down-regulation 45 HMG20B; PIAS1; PCGF1; MAZ; YAF2; CNOT3; GMNN; ZBTB11; NR4A2; USP21; BCL3; ARID5A; MED14; PIR; CHD4; TRIM32; ESRRG; CCNC; FOXD1; SERTAD2; ZNF394; TRIB3; APEX1; SREBF1; KLF10; NLK; TGFB1; IRX5; GTF3A; TOB1; VDR; BMI1; TP63; MED21; SIAH2; ZBTB18; BHLHE40; PITX1; DDIT3; RUNX3; MEIS2; ZNF331; TOX; SMAD7; SCAND1