Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11126 Osi-027 GSE70138 HME1 Human 24h 10uM EID0013
Types Number Response transcription factors
Up-regulation 138 GATA3; MYC; HBP1; MAFF; HMGA2; ZNF573; L3MBTL1; MNT; ABL1; TSG101; ZFY; SOX4; GFI1B; ZBTB16; PPARG; ZNF33B; HOXA7; CALCOCO1; WWP1; FOXO1; KDM5B; EZH1; ZBED2; TWIST1; RXRG; MAF; CREBL2; AGO2; STAT2; SUPT5H; ZNF91; ARID5A; EP300; PPP1R13L; TLE2; ZNF83; SETDB1; RELB; CDK7; ZNF667; ZNF44; MAFG; RING1; TRPS1; HDAC5; RSF1; DCC; PRRX2; ZNF611; HINFP; LITAF; MED12; ZNF250; ID4; KLF13; EED; ZNF195; SCMH1; ATOH1; ZNF623; HOXA10; ZNF239; TBX1; ATN1; ATF4; ZNF112; MEOX2; BACH2; EN1; TBX3; EGR2; AES; PBXIP1; ZSCAN18; TGFB1I1; SOX11; MXI1; NR1H4; ERBB2; ZNF544; HMBOX1; TFAP2A; ZNF160; MED13; ZNF587; KLF1; TAL1; PITX2; SMAD2; NCOR2; KLF6; ZNF117; ZNF665; RUNX1; MTA1; HTATIP2; ZFHX4; UBE2I; ZNF415; NFAT5; SHOX2; HHEX; BANP; TRIP6; PNRC1; SMAD6; TULP3; ZMIZ1; ZNF43; BHLHE41; ZNF264; HOXC10; TCF7L2; CUX1; ZNF721; NR4A2; TCF7L1; CBFA2T3; NPAS2; TCEA1; STAT3; HOXA11; IRF6; CERS4; ELF3; PLAGL1; NR1D2; AHR; BRD4; TLE1; TGIF1; GATA6; PCGF2; INSR; CITED2; VPS72; SATB1; THAP11
Down-regulation 51 CCNA2; MYCBP; SUV39H1; EZH2; GTF2A2; MYBL2; RUVBL1; CENPF; CDK2; PARP1; FOXM1; TOB1; ITGB3BP; SREBF2; TFDP1; RBM14; NKX3-1; PTTG1; ING2; C1QBP; HMGB3; PSMC3IP; TFAM; NELFB; MYCN; STAT1; BRCA1; E2F8; YWHAB; RBBP7; HLTF; MAGED1; HMGB2; FOXG1; ZBTB18; NR2F1; RBL2; ATF5; POU4F1; HMGN3; RBBP8; MYRF; LEF1; MED21; RFX5; TP63; DMTF1; BAZ1A; TOX3; MNDA; SAP30