Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11115 Bi-2536 GSE70138 HME1 Human 24h 3.33uM EID0013
Types Number Response transcription factors
Up-regulation 813 SSBP3; GATA3; E2F2; NFKB2; ZNF556; PAX8; ZNF506; ZNF778; EGR1; RFXAP; MXD1; CEBPA; CBFA2T3; FOXP3; KDM5B; SREBF2; ZBTB7C; ZNF391; DLX6; HOXC8; ZBTB43; CBL; SSX3; ZNF324B; IRF4; TAF1; ANKRD1; RFX1; CCNE1; POU6F1; ZNF253; ZNF208; PPARA; HNF4G; NKX2-5; NR6A1; CIITA; EZH1; BRDT; TAF6L; RARG; TEF; EBF2; REL; FEV; NPAS1; ZNF507; NLK; LZTS1; ZBTB44; TFDP3; GLI1; RBPJL; HES2; POU2F3; FOXO4; ONECUT1; NEUROD2; TBR1; ARID3A; EVX1; SOX30; NFE2; ZBTB39; HNF4A; POU3F1; IKZF3; CRYM; IRF5; ETV3; ATF7; FOXD3; HOXA1; PRDM9; PAX3; TULP2; PAX2; CDX4; TULP1; VENTX; TLX2; EMX1; POU3F3; SHOX; FOXL1; ZNF286A; RNF141; EYA3; ZNF814; MAPK8IP1; ZNF549; ZNF276; ZSCAN2; NR1I3; SMARCA4; BARX2; FOXH1; MAP3K10; MTA2; ZNF460; ZBTB7B; OVOL1; PAX7; URI1; ZNF221; TFAP2B; PRDM5; ESRRB; FOXJ1; MYT1L; NACA2; ASCL2; ZNF629; CREBZF; CBX2; CHD3; PRRX1; E2F8; IKZF4; WDHD1; CARF; GCM2; PARP1; LHX5; ZBTB25; PRDM2; ZFY; LMX1B; NR4A2; SRY; DYRK1B; HOXC10; ZNF550; PHOX2A; YY1; ESR1; LYL1; POU6F2; NFKBIB; PGR; DLX4; RELB; RFX2; MEOX2; NEUROG2; ZNF493; CBX8; STAT5A; TBX6; NKX6-1; ZNF442; NR2C2; ING1; JAK2; SOX21; GRIP1; GSC2; MAFK; HIC1; STAT5B; ZBTB32; ZNF764; NEUROD4; FOXN1; GFI1; KLF15; TXNIP; TAF1C; HOXC13; FOXI1; HMG20A; ASCL3; WHSC1L1; ZNF225; SCRT1; SUV39H2; EGR3; ATOH1; FOXB1; ZNF780B; GFI1B; SSX7; ID4; ZNF639; GABPB1; SCAI; RSF1; TADA2A; RFX3; TBL1Y; POU4F2; ONECUT2; ZNF41; PRDM8; CRX; ETV6; DBP; ARNT; HOXD12; ZIC4; HAND1; POU3F4; MLLT1; FOXE3; ZNF711; TBP; ZNF157; PRDM16; SSX1; HNF1A; OLIG2; ATF6B; LMO1; RARB; PML; VHL; SKI; ZNF536; YBX2; ZNF682; TLX1; DCC; GATA1; ZIM2; ZNF80; MDM2; TLX3; GBX2; HNF1B; BRIP1; ZNF695; IKZF2; KLF1; LIN28A; ZNF696; ZNF154; ZNF132; ZNF749; NR5A1; ZXDC; ZNF688; ZNF407; GCM1; ALX4; ZNF613; EHMT1; PAX1; MLXIPL; ZBTB6; SOX12; NKX2-8; NCOA1; HOXA6; ZIC3; IRX5; CREB5; ZNF614; DLX5; ZNF516; NFYB; ZIC1; PRRX2; PITX3; SIX5; ZFHX2; VAX2; WNT4; ZNF343; SOX14; MECP2; TAF7L; PAX4; NFIX; POU2F2; SP140; FOXD2; ZNF415; CUX1; SOX5; ETV2; OSR2; EN2; NEUROD1; THRB; PITX2; MSC; TAF4B; MED20; NHLH1; GTF2I; PDX1; ZNF226; TBX4; ELF3; RUNX2; ZNF81; SALL1; HAND2; MSX2; HOXB8; IRF8; NEUROG3; SMAD9; MAML1; ZNF345; ZNF529; HABP4; GLI2; SP4; AFF3; ZKSCAN8; ZNF257; ZNF224; TSC22D4; ALX3; ARRB1; PCBD1; LBX1; HOXC4; NFATC1; MZF1; ZXDB; SNAI1; FOXE1; ZNF471; KLF8; SIM1; EYA2; TRIM25; ZNF674; NEUROG1; EGR4; GTF2A1; ZSCAN18; MAML3; HOXB1; E2F3; ASH1L; MNX1; RNF14; ZFP2; MBD1; NEUROD6; CSDC2; SP1; STAT4; ZNF236; ZNF135; ZNF215; ESR2; HOXC5; ARID3B; SPDEF; SRCAP; TONSL; ESRRG; TCF4; ZNF155; ZNF770; NFATC4; TUB; TBX5; SUPT7L; ZNF107; DMRT1; JUN; UIMC1; AIRE; KLF3; ZBTB18; TFDP2; OVOL2; HOXB3; CCNH; ZNF329; GBX1; HOXC6; SOX1; ZNF710; ZNF510; GMEB1; ZNF136; HEYL; HLF; ZNF771; TCFL5; ID2; EGR2; TFAP4; ZNF701; RCOR3; HDAC11; TAL1; MDFI; TP73; IFNB1; POLR3F; ERBB4; CRTC1; ZNF223; DOT1L; LHX1; AFF4; HOXC11; MXD4; KDM4A; LHX6; HR; BACH1; ZNF79; MED31; TCF15; MSX1; MDM4; ZNF214; PHIP; POU1F1; PAX9; VSX1; ZNF480; MEOX1; ZNF75D; HMX1; SOX17; NRL; TGIF2; ZNF175; STAT2; PIAS3; ZNF8; PHF2; SIAH2; ATN1; HOXD9; THAP9; PROP1; ZNF675; KMT5A; ZNF362; POU5F1B; ZNF235; ZSCAN9; MYB; HOXA3; AFF2; NRF1; SIN3B; E2F1; SOX18; ZNF141; ZNF287; MYCN; SOX4; FEZF2; CHD2; SERTAD2; RARA; RORC; NHLH2; MAK; ACTL6B; HESX1; NSD1; PRMT2; PKNOX1; ZNF76; ZBTB3; MYOD1; STAT3; SP2; MED1; ZNF440; ZNF671; ZNF816; MEF2C; HCFC1; FOXJ2; PBX2; PRDM13; PHOX2B; ZSCAN32; TBX19; PROX1; RAX; CBX6; ZNF254; POU4F1; ZNF492; VGLL1; NAB2; KMT2A; MYOG; RORB; PURA; ZNF234; GABPA; ZNF783; MYEF2; KLF12; ZNF35; SOX10; SOHLH2; DEAF1; ZSCAN16; NR2E1; POU2F1; POU4F3; SUPT6H; RFX7; ZKSCAN7; HIVEP2; E2F5; ZNF484; YAF2; SNAPC4; GATA4; ZNF835; ZNF552; CREM; TULP4; HOXD3; HOXD13; EYA1; SMARCD3; ZMIZ2; ZFP69B; TFEC; HEY2; ZNF93; ZNF467; SHOX2; PRDM1; CEBPG; ZNF672; ALX1; UTF1; AGO2; CEBPE; ZNF212; SOX2; PRDM10; HIVEP1; ZHX3; IL16; ZNF197; ZNF384; ZNF124; TBX10; FOXC2; KMT2D; MNDA; FOXA2; CREB3L1; ZBTB40; ZNF334; TBPL1; HIC2; HOXB9; WT1; SKIL; BATF; ZNF189; PIAS2; ZBTB48; BCL11B; ZFP37; KMT2B; BARX1; SMARCA1; SUV39H1; MEN1; HOXA2; THAP3; ZNF14; ZBED1; NKX2-2; ELK4; FLI1; ZNF273; FOSB; BHLHE40; MSL3; BAZ1B; ZNF142; WHSC1; ARID4A; TTF2; EMX2; CIZ1; ZNF512B; EP400; RORA; MAFB; ZNF646; CAMTA1; FHL5; ZNF217; MLLT10; NKX3-2; APBB1; ZBTB14; ASCL1; TCEA2; PRDM14; LHX3; NR0B1; DDX54; BCL6; ZNF419; HMBOX1; TCF20; GATAD2A; BRD7; TAF7; PLAG1; ZKSCAN4; TLE2; CDK9; MEIS1; NFAT5; NR3C2; ARL2BP; CDX2; LHX2; RXRG; CHD7; TWIST1; ZNF33B; TRIM33; SIX6; MYF6; KLF4; SETDB1; TAF11; TBX1; MYF5; SMARCD1; SOX3; RUNX1; ING2; CHAF1B; ZNF331; PIR; BRWD1; ZKSCAN3; MEF2D; EED; FOXL2; HOXD1; ISL1; ERCC2; ZNF551; ZNF652; ZNF528; NCOR2; GRHL2; SOX13; HOXD10; CALCOCO1; ZNF10; CITED2; ZNF443; NAB1; PCGF2; E4F1; HIF3A; CBFA2T2; NR4A1; HOXB2; CHD1; NR1H4; ZNF669; HOXB6; BNC2; HINFP; ZNF205; PATZ1; CIR1; CBX4; ZNF787; MED6; ACTL6A; HSF4; TRIM32; YEATS4; ZNF43; SALL2; ZFHX3; ZNF587; ZNF85; LMCD1; BRF2; TFAP2C; RERE; PRDM12; PSMC3IP; PCGF3; CTR9; MYBL2; TDRD3; NANOG; KLF13; PLAGL2; HDAC9; MED12; THRAP3; ZNF34; KDM2A; ZNF195; SRF; BRCA1; RFX5; NPAT; DNAJC1; TAF9B; AATF; ARID1A; ZNF264; ZNF304; NR4A3; THRA; NR5A2; ZNF211; NFX1; TSC22D1; PEG3; MED25; HDAC4; MYCL; ZNF117; HTATIP2; ZNF423; PPARD; ZFPM2; ZNF354A; EP300; KDM5D; BNC1; RXRA; ZNF768; LEF1; DNMT3B; USF2; ZSCAN31; TBX21; SIM2; HOXA4; PITX1; BRD3; ZNF667; HSF2; REPIN1; ZNF222; BHLHE41; HDAC5; NOCT; FUBP1; NFE2L3; ZNF227; GATA2; ATF7IP; NR0B2; TFCP2; ZNF606; ZNF350; EPAS1; EHMT2; KLF2; VDR; NKX2-1; CREB3L2; ETV5; TRIM22; ZEB2; TRAK1; FOXC1; ZFHX4; JARID2; IRF6; NR2F1; TAF1A; ETV1; HSBP1; CUX2; ZNF165; JUND; JUP; EHF; PLAGL1; TBL1X; SMAD2; BCL11A; DACH1; MAF; ZNF586; TBX2; TBL1XR1; DMTF1; VPS72; SLC2A4RG; NR3C1; RUNX3; AEBP1; SIX3; TLE1; TCF7L1; ST18; HOXA11; MYRF; SATB2; HOXA10; THAP11; ZNF589
Down-regulation 236 FOSL1; RHOA; YBX3; TCEB2; HIF1A; CDK2; USP22; VGLL4; IKBKAP; MYC; LOXL2; MTDH; APEX1; CCNA2; EZH2; PA2G4; ZBTB11; SP110; RBM39; RNF138; ATF4; C1QBP; CRK; PPRC1; THAP4; XRCC6; UBE2I; ENO1; LITAF; ENY2; HES1; ATF1; NFIB; NONO; PTTG1; RUVBL1; ZMIZ1; NCOR1; RAN; GTF2A2; PSIP1; SF1; HNRNPD; PTRF; FLNA; SUZ12; CCNC; CDC5L; ZNF32; ZNF593; HDAC2; GTF3A; NEDD8; HDAC1; TSC22D2; NFIL3; TAF1D; MAZ; BTF3; PQBP1; DEK; CBFB; NACA; ZMYM2; RUVBL2; HMGB1; DNMT1; ZNF232; TRIM27; NCOA4; HMG20B; GATA6; MAFF; BTAF1; BCL3; MED15; TRIM28; CTNNB1; PSPC1; RLF; SP100; DRAP1; NPM1; NRIP1; PBX3; SND1; MNT; MXI1; MMS19; YWHAB; MYCBP; PCGF1; TCF7; FOXF1; CREG1; TCF12; YBX1; CSDE1; SSRP1; VEZF1; PUF60; CNOT1; DDX5; ZNF292; ZFP36L2; TFAM; NR1I2; ZBTB1; RBM14; ZNF410; DDX17; SMARCB1; CERS6; ZNF263; RBFOX2; MED27; BRD8; SNW1; HDAC3; PAXBP1; JUNB; NELFB; KLF7; SOX9; RYBP; ZNF12; CTCF; CENPF; ZMYND8; CNOT2; HMGB3; ZFX; TOPORS; WDR77; ADNP; CEBPD; RBPJ; TOX; SREBF1; CNBP; DDIT3; IRF2; CEBPB; TBX3; RNF6; ARNTL; NR1H3; ATF5; ZNF544; CTBP2; ETS1; REST; TFAP2A; SAP30; NFKB1; PBX1; TOX3; ZNF84; DR1; ARNT2; CDYL; TRIB3; WWTR1; ZNF432; KDM4C; SETD3; UBE2L3; CALR; SSBP2; PFDN5; CREB3; STAT1; ZNF131; CARM1; AES; PEX14; CBX3; C1D; USP21; AIP; ATF3; PMS1; TCEA1; KLF9; AHR; ZNF83; PRKDC; ZNF219; MTA1; FOXM1; MED17; CHD8; ZNF562; TRIM16; SFPQ; PIAS4; TADA3; BBX; TGFB1I1; TRIP6; HIRA; HOXA5; KLF5; GTF2IRD1; ZBTB38; THAP10; ZNF146; LDB1; ARNTL2; RBBP4; MECOM; CTBP1; IRF7; MED13; BTG1; SIX2; TGIF1; TGFB1; KLF6; IFI16; BASP1; ABL1; CEBPZ; ZNF721; ZNF274; SUB1; NR1H2; MAGED1; MTF2; PHF20; NKX3-1; ETS2; HMGA1; MEIS2; ZFP36L1; ID1