Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11109	Saracatinib	GSE70138	HME1	Human	24h	10uM	EID0013

Response Information :

Types	Number	Response transcription factors
Up-regulation	102	NFKBIA; CEBPD; TSC22D3; CREG1; FOXO3; FOXO4; SREBF2; HDAC6; SMARCD2; FOXJ3; HOXA5; SSBP2; PCBD1; GRHL2; WNT4; VGLL4; PRDM2; ZNF91; ZBTB16; RELB; TP53; ZSCAN31; ZSCAN18; HMGN3; ZMIZ1; OSR2; ARID5B; TRIM29; BCL6; NR2F1; ING4; RXRA; SREBF1; NFIB; ZNF667; PBXIP1; TLE2; TCEA2; PITX1; ZNF219; SMAD1; HBP1; PBX1; TXNIP; MKL2; LITAF; KAT6B; TRPS1; SPDEF; AIP; ERBB2; CREBL2; RFX5; MXD4; EHMT2; BTG1; STAT3; AR; ZNF43; ASCL1; IRF6; CTBP2; CBFA2T3; PCGF2; FOXA1; WT1; MTA1; HEY2; SALL2; PNRC1; SMARCD3; INSR; SOX13; IRF9; MAF; TP63; JUND; ATF3; KLF4; ESR1; BACH2; TLE4; ERBB4; JUP; TOB1; ELF3; PHF20; MEIS1; MXI1; ELF5; TSC22D1; SOX11; BCL11A; TCF7L1; BRD4; KDM5D; PEG3; MAFB; TOX; TLE1; MEIS2; THAP11
Down-regulation	59	FOSL1; HMGA2; CCNA2; SUV39H1; EGR1; HES1; ELK3; DRAP1; PPRC1; CENPF; KMT2B; BRD7; WDR77; ZNF146; MYBL2; HMGB1; TMF1; RBM14; KDM5C; BMI1; XBP1; SSX1; DNAJC2; BIRC2; CBFB; TGFB1; HMGA1; MED14; CRY1; JARID2; HOXA1; CREM; SMAD7; WWP1; MYBL1; ARNTL2; MAGED1; ZBTB18; LOXL2; JUN; FOXD1; SIM2; MNAT1; BCLAF1; HOXB7; BASP1; TSC22D2; ZMYM2; MYRF; ZEB1; ZNF652; BHLHE40; CD3D; EGR2; NRIP1; ZBTB38; EGR3; SATB2; ZNF423