Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11097 Gsk-1059615 GSE70138 HME1 Human 24h 0.12uM EID0013
Types Number Response transcription factors
Up-regulation 60 SOX4; HMGA2; VGLL4; CALCOCO1; NFYC; FOXJ3; ZNF281; HDAC6; BAZ2A; SP110; HBP1; EZH1; BAZ2B; RERE; BATF; NFE2L1; CAMTA1; SP100; SMARCC2; ZNF711; STAT6; SOX10; HDAC5; AES; MED13; AHR; DDX17; ZIC1; TFEB; MAGED1; SOX11; BTG1; ZFPM2; ERBB2; IRF9; CSDE1; CHD7; TRIM22; MEOX2; ZFP36L2; BRD2; NR1D2; HOXB2; ELK3; SALL2; TGIF1; ZBTB16; PNRC1; BRD4; SMARCA2; PAX5; ZBED2; BACH2; TOX3; KLF6; PEG3; INSR; BASP1; POU2AF1; TLE1
Down-regulation 37 CCNA2; RUVBL1; SSRP1; MECOM; FOXG1; FOXF1; MYBL1; NR1H4; CBFB; TCF21; FOXM1; TCF12; CREM; ATF5; TAL1; ISL1; HOXD11; POU4F1; MEIS2; PITX1; CCNE1; BHLHE40; NR0B1; EYA1; TEAD4; NKX3-1; SMAD6; TBL1X; TRIM16; SIX2; PPARG; ZNF331; TRIB3; WT1; HOXA11; BHLHE41; ID1