Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11055	Tie2-kinase-inhibitor	GSE70138	HA1E	Human	24h	3.33uM	EID0114

Response Information :

Types	Number	Response transcription factors
Up-regulation	63	GATA2; NRIP1; PAX8; ZNF512B; MTDH; AFF1; ATF1; NCOA4; BHLHE41; RAN; NR1D2; MXI1; SUZ12; TSC22D2; ENO1; KAT6B; HSF2; AHR; SMARCA2; HMGA2; TBL1X; RBPMS; SLC2A4RG; BMI1; ECD; ZNF468; PDLIM1; SUB1; PCBD1; HNRNPD; ZNF226; PRKDC; HMG20B; CTBP1; CBX3; ZNF432; IKBKAP; ID2; SMAD3; ZEB2; TCERG1; TBL1XR1; PIR; FOXC1; FOXJ3; HLF; RUNX3; MYCBP; KDM5D; NFIB; NUP62; TRIP6; HTATIP2; EDF1; SMAD2; EMX2; SAP30; HOXC6; MSX1; ID4; TBX3; ZBTB38; NR1H2
Down-regulation	63	MEIS1; ZMIZ1; WNT4; LEF1; RUNX1; KLF10; HES1; PRDM2; PCGF1; NR2F6; FOXA2; KLF7; SPIB; CALR; BACH2; PAX5; TOX; SSBP3; CERS6; IRF9; SRCAP; OVOL2; AEBP1; IRF6; ZIC1; NEUROD1; BTG1; TP63; ELF4; GRHL2; BNC2; CD3D; TOX3; SPDEF; HMGB3; TULP3; TOB1; NFATC4; FOXF1; KLF13; GATA6; ATN1; POU2AF1; JUNB; BCL11A; NKX2-2; ELF3; NFE2L2; DLX2; ETS2; CBFA2T3; ZFPM2; EHF; ZNF264; ZNF423; HOXA5; MYBL1; STAT1; PEG3; ETS1; ZNF91; GLI2; ERBB4