Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11028	Regorafenib	GSE70138	HA1E	Human	24h	0.12uM	EID0114

Response Information :

Types	Number	Response transcription factors
Up-regulation	110	HMG20A; CNOT3; PML; MNAT1; SMAD7; TBX3; CAPN15; KMT2B; ZNF211; ZNF282; KLF13; MED20; ID3; IRF3; MEF2A; FOXG1; FOXA2; CBX4; CALR; CBX6; EZH1; BAZ2A; RNF111; ZNF276; C1QBP; PRDM1; TGFB1; TLE2; NLK; NFAT5; PROX1; MED25; ZNF24; HES1; SUZ12; AIRE; TRIM25; AES; SUPT3H; TCFL5; MSC; PIAS1; ID4; JUP; HLX; CENPB; SATB2; ZNF580; E4F1; TRIM28; MAP3K10; CDK8; IRX4; CDX2; SMAD1; CDX1; SMAD6; FOXF1; RAD21; ARID3A; VPS72; DMTF1; HMGB1; DACH1; BAZ2B; ATF3; CHD9; GFI1; CUX1; LYL1; TULP3; SMARCB1; ATN1; SSBP2; ATF5; RARG; KDM5C; KLF5; SRCAP; EPAS1; TDP2; MYRF; MLXIP; PPARD; PRDM14; PITX2; ZNF160; NFATC4; SPDEF; ST18; ZNF124; HMBOX1; CREB1; GLI2; ZKSCAN1; SOX9; BCL11A; CBFA2T3; ID1; CUX2; SNAI2; HIRA; ERBB4; HEY1; POU2AF1; FOXF2; ZNF423; IRF6; ASCL1; ZNF117
Down-regulation	70	TCEA2; RFX5; TAF1D; NPAS2; ZNF184; RBBP8; MECOM; BAZ1A; TGS1; BASP1; ZNF23; PHF1; STAT5A; FHL2; PBX3; CEBPB; SOX17; MNT; PLAGL1; IFI16; NFKBIA; HOXB6; KAT7; PHF20; DNMT3B; SPEN; PCGF2; PLAG1; KLF2; HTATIP2; LPIN2; SMAD2; STAT6; SCAND1; TSC22D2; ARID4B; HOXB2; LMCD1; NFIB; SIAH2; HOXB7; PRKDC; CTR9; TCERG1; ZNF43; HMGB2; ADNP2; MNDA; RUNX3; DAXX; TBL1XR1; FOSL2; CREB3L1; HNRNPD; KDM5D; EGR3; SOX11; FOXO1; HOXC6; YWHAB; MYBL1; TBL1X; HOXD1; HOXA5; ZNF532; BHLHE41; GATA3; ZBTB38; ETS1; WT1