Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11026	Regorafenib	GSE70138	HA1E	Human	24h	1.11uM	EID0114

Response Information :

Types	Number	Response transcription factors
Up-regulation	60	E2F2; BIRC2; ZMIZ2; ENO1; RBBP4; ZBTB43; KDM5D; ELF5; REPIN1; MSX1; SOX4; TMF1; BATF3; BMI1; CBX3; MTF2; ANKRD1; TBPL1; NFKBIA; HSF2; FOSL1; CTR9; ATF4; SIX1; BHLHE40; MED24; HNRNPD; TBL1X; CRY1; TRIM16; HLTF; TRIP6; SMARCA2; PIAS2; FLNA; DRAP1; ZNF468; NR1D2; CREG1; HMGN3; ZBTB38; TAF10; EDF1; GATAD2A; WWC1; TBL1XR1; HTATIP2; NR1H2; FOXC1; SUB1; PTTG1; MAFB; WWTR1; IFI16; STAT1; DMTF1; CRK; MAGED1; PUF60; HOXC6
Down-regulation	145	NR2C1; HIC2; THAP7; INSR; ZFP36L2; HIPK2; ZNF423; LZTR1; RBFOX2; RREB1; HOXB6; MED15; IKZF2; SETDB1; TRIB3; ZNF552; ELF4; MED14; CD3D; NCOA2; PAX5; NR2F1; FOXA1; KLF3; TFDP2; ZNF816; SOX3; PKNOX2; SPDEF; ZFPM2; PFDN5; SSBP3; ZMIZ1; CEBPD; TTF2; ZNF273; ZNF75D; HOXD1; KLF7; NKRF; SOX13; BNC2; BRWD1; NEUROD1; ZNF74; ZIC3; HOXB2; ZNF557; MAML1; PAXBP1; TCF7L1; SMARCB1; HES1; POLR3C; ATOH1; FUBP1; LHX1; CNOT2; E2F8; NR1I3; TCEA2; PRDM14; MED12; IRF6; ZNF141; ZNF12; TERF2; HOXC4; NFATC4; HLX; CBFA2T3; MYRF; ZSCAN9; HOXB5; ZNF195; TGIF1; MECOM; ZBTB3; PCGF3; LIN28A; VPS72; JUP; ATF3; MKL2; PBX3; SSBP2; BNC1; BACH2; ZIC1; ZNF117; CHD7; TP63; SUPT3H; PEG3; NANOG; TRPS1; MEIS2; OVOL2; TP53; PAX6; NR5A2; NHLH1; CREM; SPIB; SRCAP; ZNF85; FOXF2; CUX2; AEBP1; BARX1; CCNH; NFE2L2; ZNF232; TOB1; MYB; ZNF665; POU4F1; ZBTB16; POU2AF1; ARID5B; EPAS1; OSR2; ZNF623; ELF3; MYCN; ERBB4; NFE2; ZNF544; TFAP2C; ST18; SALL2; ZNF573; ZBED2; GATA6; TCF21; CREB1; BCL11A; HHEX; ID1; ZNF264; NR4A2; WT1; TXNIP; HOXA5; ETS1