Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10981	Alectinib	GSE70138	HA1E	Human	24h	0.04uM	EID0114

Response Information :

Types	Number	Response transcription factors
Up-regulation	92	IRX5; RBBP5; TMF1; PREB; MED1; ENO1; HSF2; MAX; KDM5D; ING3; NR1D2; ATF1; ZEB2; BAZ1B; BRD2; TSC22D2; TADA3; ZNF148; KDM2A; HNRNPD; BATF3; MBD2; UBP1; SATB2; FOXC1; SFPQ; CREB5; ZBTB38; MSX1; EDF1; SUZ12; RNF111; ZBTB11; RBM14; SMARCD3; ZKSCAN7; PBRM1; ZBTB43; CTR9; RFX5; ERBB2; MAFB; USF2; SCAND1; PTTG1; SLC2A4RG; RBBP4; HCFC2; BBX; HTATIP2; IRF2; TRIM28; TCERG1; YBX1; CREG1; FHL2; SMAD3; TAF10; BAZ1A; HMGN3; BMI1; CCDC59; MED24; FLNA; PIAS2; NEDD8; KMT2A; HOXA5; SMAD2; HLTF; ID2; GATAD2A; SMARCA4; ATF4; CRY1; RUVBL2; NFIB; CBX3; APEX1; NR2F2; HMG20B; WWTR1; MAGED1; SALL1; HOXC6; PURA; TRIP6; TXNIP; ZBTB18; ZBTB20; NR1H2; PUF60
Down-regulation	228	ARNT2; TRIB3; ZNF133; ATF3; PBXIP1; ZNF536; ZNF467; OVOL2; TTF2; FOXA1; TCEA1; FOXG1; ZNF33B; FOXA2; HDAC9; VGLL1; HOXB2; CIR1; SOX12; NR2F1; BNC1; ZNF239; NR5A2; IRF6; PRDM14; GBX2; KLF3; ZNF768; PAX5; TP63; ZNF557; SETDB1; NEUROG2; HOXB6; FUBP1; HIC2; KLF9; SREBF1; CERS4; SPIB; ELF4; HOXD1; CBX2; ZNF75D; CALCOCO1; FOXO1; TAL1; SOX13; ARID3B; TLE2; GATA6; SOHLH2; ELF3; HSF1; RARG; ZSCAN2; HOXC13; TFDP3; HOXB13; HOXC11; TCF4; CNOT3; SRY; ONECUT1; SSBP2; LIN28A; GRHL2; ZIM2; ARL2BP; NEUROD1; MAML3; MED25; POU6F2; NFATC4; ZNF74; POU4F3; RAD21; SUPT3H; ZNF219; HOXD13; ZNF350; TGFB1I1; SIX3; SOX14; FOXE3; CENPB; ZNF423; NCOA2; AIRE; ZNF394; ZBTB16; CEBPD; KLF1; GATA1; ZNF682; JUNB; ZNF141; PTRF; FOXH1; MYCL; CHD2; TBX21; ST18; MED12; SOX3; ZNF154; TCF21; OLIG2; THRB; BARX1; EMX1; NR4A3; BNC2; ZFP36L2; CBX7; MEIS2; POLR3C; E2F8; HIPK2; TEAD3; ARID5B; CDIP1; BRD4; ZIC3; ZNF444; BRDT; TLX3; TFAP2C; LDB1; ZNF695; DLX4; IRX4; ZNF215; HOXB5; TP73; JUP; EN1; ZNF778; CD3D; THRA; NFE2L3; SRCAP; HBP1; TERF1; CTBP2; SPDEF; TOX3; NR2F6; CSDC2; CALR; CDX2; SATB1; NKX2-2; NR1H3; FEZF2; MYRF; HOXC4; SSBP3; KLF13; SIX6; HLX; EHF; NEUROD2; HOXD3; FOXF2; TDP2; SOX2; PEG3; OSR2; NANOG; LITAF; TGIF1; ZNF665; BACH2; SALL2; MYBL1; ZNF415; KLF5; NR0B1; EPAS1; KDM5C; AEBP1; TRPS1; BRWD1; POU4F1; GFI1; CCNH; NKX2-1; SNAI2; CREM; VPS72; ZNF623; STAT4; AR; ZNF195; CBFA2T3; ZNF117; CRYM; INSR; IKBKAP; ID1; ZNF500; TOX; NFE2L2; POU2AF1; DLX2; ZNF573; SMARCA1; TFAP2A; ZNF331; NUP62; FOS; ZNF532; CUX2; TBX3; ERBB4; IRF9; ZFPM2; BCL11A; REL; ZNF91; DACH1; ESR1; INSM1; ZIC1; WT1; STAT1; GLI2