Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10976	Alectinib	GSE70138	HA1E	Human	24h	10uM	EID0114

Response Information :

Types	Number	Response transcription factors
Up-regulation	66	FOSL1; DDIT3; HMGA2; SP100; CDC5L; VGLL4; MTDH; HMGA1; MLX; TRIM33; BIRC2; AATF; E2F3; STAT1; TSC22D1; ZZZ3; BHLHE41; TDP2; ZNF202; MED27; ZNF23; GTF3A; BCL10; ZNF281; MECOM; CHD7; TDRD3; BRD4; GTF2IRD1; BANP; SOX10; STAT5A; KLF6; TGS1; RNF6; TCEA1; ZMYM2; ZNF721; MXI1; SAP18; ZNF611; ZNF160; COPS5; HDAC9; TRIM27; BRD2; ETV5; NUP62; TCERG1; NR1H3; RUNX3; CD3D; CEBPG; PIR; HTATIP2; PDLIM1; ZNF195; ZNF468; TCF7; SMAD1; ETS1; STAT3; IFI16; ATF4; NKX3-1; PUF60
Down-regulation	79	MYBL2; PBX1; CDK2; MEIS1; SOX12; SREBF2; LMCD1; SIM1; CALR; CCNA2; TLE4; TAF9B; HOXA10; BRIP1; TCF4; WDHD1; ZMIZ1; STAT6; E2F8; PBXIP1; CBX5; HMG20B; FHL2; ETS2; ZNF512B; ID3; NR2F1; NFIB; CENPB; OSR2; PITX2; RNF141; ID2; MYCBP; AEBP1; SLC2A4RG; ATF5; TSC22D2; IKBKAP; ZFP36L2; HMGN3; TCF7L1; CREB3L2; PLAGL1; SOX4; MYCN; JUND; ID1; NEDD8; PBX3; TCF21; SMAD3; CALCOCO1; KLF4; TULP3; RBPMS; HMGB3; HOXC4; CUX2; TOX3; HDAC6; SMAD6; ZBED2; ID4; PRRX1; HOXA5; HOXC6; LEF1; MYB; ARID5B; GATA6; MAGED1; SMARCA1; TRPS1; ZBTB18; CITED2; GLI2; FLNA; MEIS2