Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10952	Dabrafenib	GSE70138	HA1E	Human	24h	0.04uM	EID0114

Response Information :

Types	Number	Response transcription factors
Up-regulation	77	KAT6A; HSBP1; DLX5; CCNE1; CEBPA; RNF6; HMG20A; HOXB13; ZNF16; SMARCC2; SOX15; ETS2; CALR; ZNF282; CDK8; CRYM; NR3C2; NFATC3; ZBTB16; HSF1; TRIM24; HOXB5; TERF2; YBX2; PPARGC1A; CREBZF; ATOH1; HMBOX1; OSR2; ARID1A; RXRA; TAF1D; ZFP36L2; CDX1; TP63; ZKSCAN1; HTATIP2; TLE2; TBX3; IRF6; ASCL1; TSC22D2; TDP2; NCOA2; MYCL; WNT4; HOXB6; ZSCAN18; CTBP2; MLXIP; TCF7L2; HMGB1; SMAD1; NFAT5; NR1I2; PDLIM1; NKX2-1; PURA; FOXJ3; BCL11A; MYCN; CUX1; ID3; ZNF623; ZNF160; FOXO1; SSBP2; ID1; TP53; ZNF544; TOX3; FOXF2; NFATC4; LITAF; TCF7; SNAI2; TXNIP
Down-regulation	63	HDAC2; SOX11; ZFP36L1; RFX5; GON4L; UBE2I; ZBTB24; ZNF423; GTF2IRD1; ANKRD1; TEAD1; PTRF; BNC2; MEF2A; PSMC3IP; CDK2; HMGB2; ZNF32; ZFPM2; KDM5D; SHOX2; ZMYND11; BMI1; KLF2; HSF2; HMGN3; MNDA; TEAD4; RFXANK; SUB1; RBBP8; FOXG1; ETV5; HLF; CTBP1; MEIS2; NR2F1; KDM2A; SOX17; TRIP6; NFKBIA; LMCD1; ATF4; IRF8; SOX9; WWC1; ZEB2; PITX1; FLNA; CREB3L1; MAGED1; LEF1; ZNF226; TCF21; MBD2; IFI16; HHEX; FOSL2; NKX3-1; NR2F2; ETS1; WT1; GLI2