Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10825	Tie2-kinase-inhibitor	GSE70138	HA1E	Human	24h	0.12uM	EID0113

Response Information :

Types	Number	Response transcription factors
Up-regulation	114	TBX2; NFATC3; BRCA1; AFF1; RXRA; RHOA; IRF1; SAFB; SERTAD2; SKI; SAP18; SREBF1; TXNIP; RUNX1; PHF2; KLF9; MGA; HDAC4; ZBTB38; FOXC1; TFEC; PMF1; TEAD1; EP400; HIPK3; SND1; NR1D2; EMX2; MEIS1; HLTF; NFIB; SMAD2; ZHX3; DNAJC2; ADRB2; WWC1; MITF; DPF2; WHSC1; DNAJC1; BAZ1B; TCF4; MYCBP; CUX1; ZBED4; NKX2-2; MYCL; PDLIM1; FOXA1; FOSL2; DMTF1; ZNF587; BMI1; POLR2A; RNF141; MED27; CTR9; EZH2; PCBD1; BRD8; FOXN3; BCLAF1; ID2; ZNF227; CERS6; PHIP; BHLHE41; IKBKAP; TRIM16; TOPORS; ERBB2; SMARCA5; ATF7IP; JARID2; BCL3; MYCN; NCOR2; BATF3; STAT1; ETS2; ZNF711; NFAT5; HOXB2; NPAS2; RBM14; MECOM; SFPQ; SALL1; HOXA10; ID3; HDAC1; GRHL2; PIR; HTATIP2; MED24; NKX3-1; ID1; SMARCA2; ZMYM2; EHF; ZEB1; TOB1; FOXD1; CRY1; E2F8; KDM5D; MSX1; CREG1; SOX9; HMG20B; PBX1; ZSCAN18; ST18; ABL1
Down-regulation	130	MXI1; SUPT5H; ZFP36L1; UBE2I; ATN1; RXRG; MEIS2; THAP11; KLF15; CCNC; TCEA1; MDM2; ID4; HOXC4; SMARCD3; POU5F1B; ZEB2; PITX2; ZNF32; MED15; ENY2; HOXD9; ZNF611; ATF2; PRMT2; BTG1; PRDM12; TAF11; CAPN15; TAF5L; TBPL1; CALR; SUPT3H; MEOX2; ZZZ3; SOX10; RAD21; FOXG1; ZNF430; MMS19; POU2AF1; THAP7; ZNF573; EP300; ZNF580; CBX5; TCF7L1; EYA2; TRIM29; ZFHX4; PRDM14; ELF1; ZNF589; PEX2; DLX2; LIN28A; SIX3; SHOX2; FUBP1; CERS4; TGIF2; SP3; CITED2; RAN; THRA; PAX5; BNC2; HOXB1; TAF7; JUND; LYL1; MAFB; TERF1; MYBL1; NFE2L3; ZNF44; ISL1; IFI16; CARHSP1; EYA1; PIAS1; TBX3; SSBP3; LDB1; FOS; ZNF654; ZNF12; TP73; NKX2-1; RARG; BACH2; NFKB1; ZFPM2; POLR3C; ZNF467; SALL2; HDAC9; NANOG; ZNF500; HMGA1; ARID5B; CHD9; SOX11; CEBPD; EN1; FOSB; EGR3; HOXC6; DDIT3; ZBTB18; GATA6; ESR1; CEBPB; TOX; PRRX1; GLI2; ZNF160; REL; ASCL1; ERBB4; HES1; HIRA; ZNF423; SMAD7; HIC2; NFATC4; ZNF232; BCL11A; OSR2; PEG3