Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10824	Tie2-kinase-inhibitor	GSE70138	HA1E	Human	24h	0.37uM	EID0113

Response Information :

Types	Number	Response transcription factors
Up-regulation	86	ETV1; BRCA1; ZMIZ2; DDX17; RBPJ; PPARG; ZNF384; HAND1; RHOA; MNX1; ASXL1; CDYL; LZTS1; NFIL3; HEY1; IKZF1; ZNF215; IRF8; MAF; ZFHX4; HOXB6; BTF3; MYCL; CAMTA1; TFDP2; CREBL2; MXD3; MLX; ZIC3; TAF9; TTF2; NR1I3; APEX1; TFEC; ZNF85; RBFOX2; INSM1; MITF; PTTG1; PAX6; HOXB5; ATF7IP; EZH2; NHLH2; SMARCB1; NUP62; NKX2-1; NR1H3; BATF3; MYCBP; ARID4B; CBX6; NR2F2; LIN28A; NR5A2; CRYM; LITAF; IRF4; KAT7; KLF5; SPIB; IRF6; FOS; HOXB13; FOXG1; GATA6; FOSL2; CREG1; SIX3; KDM5D; BACH2; ZNF721; TFAP2C; SNAI2; PBX1; ZNF331; ARID5B; MKL2; TXNIP; FOXF1; GRHL2; NEUROD1; BCL11A; HMG20B; PSIP1; GLI2
Down-regulation	75	ZFP36L1; THAP11; FHL2; TOB1; NR4A2; ID4; WWTR1; RNF141; CEBPB; RCOR1; TGFB1; TCEA1; ZNF512B; CEBPG; TSC22D4; KMT5A; POU2AF1; SMAD1; NRBF2; IRF9; FOXJ1; MXD1; PRKDC; KLF2; NPAS2; EP300; JUNB; TSC22D2; ZNF551; SOX17; ERG; TMF1; URI1; TERF1; YWHAB; PAWR; AEBP1; BAZ2B; ZNF131; MAGED1; EYA2; MLXIP; SPEN; ANKRD1; SCAND1; CITED2; HIPK3; VEZF1; TAL1; SMARCA1; SAP30; ZMYM2; NR2F6; IKBKAP; STAT1; ZNF217; ETS2; ZNF165; RUNX1; SATB1; BHLHE41; EDF1; KAT6B; CREB1; WWC1; ELK3; DMTF1; ATF5; TRIP6; FLNA; NFE2L2; SMAD7; ZSCAN18; PEG3; ZNF274