Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10746	Alectinib	GSE70138	HA1E	Human	24h	0.37uM	EID0113

Response Information :

Types	Number	Response transcription factors
Up-regulation	98	TEAD1; RBBP4; RBBP5; TBL1X; BRD3; EDF1; CENPF; WWTR1; PTTG1; NEDD8; TFAM; IKZF5; KAT7; SSRP1; PBX1; FLNA; HSF2; REST; MYCBP; ZBTB38; TBP; KMT2A; PSMC3IP; SETD2; SAFB2; FOXC1; EYA2; MLX; KDM2A; RNF141; NRIP1; NONO; TRIP6; CARM1; ERBB2; POLR2A; MSX1; NELFB; CSDE1; NFKB1; MEIS1; HLTF; TAF10; UBP1; MAF; AFF1; BRD8; ELF1; PURA; PIAS3; ZNF516; DMTF1; RBL2; SMAD3; PITX1; HDAC1; TRIM16; BMI1; KLF5; CHD1; CEBPZ; BBX; RBM14; ATF1; VEZF1; CBFB; SIM2; SF1; HNRNPD; CTR9; HOXB7; ELK3; IFI16; FOXO1; MED1; TSC22D2; ID2; PEG3; BATF3; ING3; NR1H2; HMGB2; NR1D2; PCGF2; ENO1; KLF6; HTATIP2; BTG1; SUB1; TGFB1I1; SMARCA2; RFX5; NKX3-1; CREB1; CREG1; ABL1; PSIP1; KDM5D
Down-regulation	275	ARNT2; SOHLH2; AEBP1; MYT1; OLIG2; OVOL1; ZXDC; HOXC5; SHOX; CARF; HDAC9; ZNF180; ZNF444; SRY; CTBP2; KLF15; WT1; HIRA; HOXD1; FOXK2; ZFPM2; NKX2-1; BRDT; ZNF467; KLF13; DBP; ZNF768; TULP2; ZNF816; SP3; THAP10; VENTX; POU4F3; ZNF629; CBX7; MAML3; ATN1; ZIC1; TLX3; ACTL6B; IRF9; ZNF423; CRYM; ZNF22; ZNF257; TEF; PRDM5; POLR3C; SNAI1; SAP130; MLLT1; ZNF571; ST18; SOX1; ZNF350; ZNF787; ZNF221; GATA6; ZFP36L2; ZNF557; NEUROD2; NEUROG2; HOXD11; ZNF480; VGLL1; NR5A1; PAX1; KLF4; CCNH; VPS72; HOXD13; CDX1; SPIB; LHX3; NFE2L3; ZBTB3; HNF4G; ERCC3; HDAC4; DOT1L; ZNF695; CUX2; GFI1; ZNF12; ZNF223; GATA1; CBFA2T3; ZNF43; TAF5L; CD3D; POU2F3; TAF4B; EMX1; HNF1B; VHL; PHF20; ASCL2; ZNF225; FOXD3; TP73; KDM4C; HIPK2; HOXD12; ZNF550; ZNF215; ZNF536; AFF2; OVOL2; ZNF10; ZNF85; ZNF674; HOXB13; SCRT1; TFDP3; CDX2; MKL2; NEUROD1; ALX4; NR1H4; CNOT3; PROX1; ELF4; ETV3; ATOH1; SUPT6H; GSC2; ZNF407; ZNF140; ZNF682; ZNF749; TRIM24; SOX14; PMS1; ZNF75D; HOXB1; ZNF440; PPARA; ZNF81; ESRRG; TBR1; FEZF2; PRDM9; ZNF141; ZNF80; POU1F1; EN1; PRRX1; ZNF345; CRX; SNAPC4; GCM2; RNF138; RORC; CNOT2; ZBED4; ZNF235; ZNF492; HSF1; PRDM12; TOX3; ZNF154; CHD2; TFCP2L1; HOXD3; MYB; CBX2; FOXA2; TERF1; ZBTB16; PITX2; THRB; NFATC1; RARG; IRF3; ZFHX3; SMAD7; TRPS1; HOXC13; SATB2; ZNF529; MYCL; TCF7L2; ZNF273; GCM1; ZNF195; SOX18; POU6F2; PAX4; NR2E1; NCOA2; CSDC2; TOX; ZNF544; TCF21; ZNF331; PRDM2; TRIB3; TEAD4; CERS6; KLF7; INSR; SIX3; PFDN5; TCEA1; ZMYND8; SHOX2; SSBP3; PRDM14; TWIST1; CEBPE; ZNF701; TDP2; VDR; LIN28A; STAT4; ZNF573; CBX4; HIC2; BRD4; GTF3A; DLX5; ELF3; EPAS1; CALR; ZIC3; CBFA2T2; ZNF74; ZNF33B; MYRF; TLE2; SSX1; EYA1; NFATC4; CDC5L; ZNF239; MNDA; SRCAP; TFDP2; IRF6; NKX2-2; EMX2; SOX9; ZNF623; ERBB4; CDIP1; NFE2; ZNF44; TCF7L1; JUP; ZNF415; JUNB; ZNF500; GRHL2; HES1; OSR2; FOXG1; NR0B1; ASCL1; CREB3L1; SOX11; ATF3; ZNF264; NFE2L2; TSC22D1; GLI2; MYBL1; STAT1; BCL11A; DACH1; SNAI2; ZNF665; ID1; ZNF91; ESR1; ZNF274