Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10744	Alectinib	GSE70138	HA1E	Human	24h	3.33uM	EID0113

Response Information :

Types	Number	Response transcription factors
Up-regulation	79	HSBP1; CSDE1; CEBPD; PTTG1; NR2F2; MED23; RRN3; UBE2B; PHF2; UBP1; MED21; MEIS1; TSC22D2; HSF2; TOPORS; BCL11B; CALR; RBBP5; TRIM16; ACTL6A; NR4A1; HOXC6; SMARCA4; NEDD8; CUX1; BCLAF1; ARID4A; ARID4B; CEBPB; ITGB3BP; RNF141; CD3D; TADA3; PURA; USP22; CREM; PIAS3; ID2; ZBTB38; CARHSP1; CRY1; SUB1; MAFB; TBL1X; RBL2; GATAD2A; CBFB; NR1D2; EED; PHF8; RBBP4; TFAM; CENPB; FOXF1; BMI1; SCAND1; CITED2; SIX1; CTR9; MSX1; DLX2; TAF10; MTA1; TOX3; FOXN3; EDF1; NKX3-1; HLTF; STAT1; FOXD1; SMARCA1; ELK3; PITX1; CHD9; FLNA; KLF2; TXNIP; ABL1; ASCL1
Down-regulation	148	PUF60; ZNF7; ZNF34; ZNF16; PRPF6; HSF1; KLF13; NFE2L3; MYCL; TERF1; NR1I3; OLIG2; SMAD6; VDR; HOXD10; HIPK2; ZNF623; WT1; ZNF195; PPRC1; MED12; POU4F1; ZHX2; ENY2; ZNF12; ARNT2; HOXB1; NR1I2; ZNF250; FOXG1; ERBB4; SOX18; SNAPC4; IRF2; HDAC9; PRDM12; MMS19; NAB2; VENTX; SRY; ZNF589; KAT2B; ZNF423; PROX1; HMGA1; TEAD4; ZNF124; EMX1; TCEA1; MXI1; NFIX; TP53; ZNF430; CIR1; ZNF107; HOXD1; PAXBP1; GTF3A; TRIM22; AEBP1; EGR2; ZNF557; LZTS1; ZNF682; MAGED1; FOXH1; TWIST1; ZNF273; TBX1; BRD4; ELF3; PRDM2; SOHLH2; HEY2; SOX10; CERS6; NR2F6; KLF5; ARID5B; NANOG; NR5A2; MYB; FOXI1; MYRF; SOX17; NCOR2; BHLHE41; EGR3; FOSL2; ZNF141; POLR3C; VPS72; TCF7L1; SMAD1; EMX2; HEY1; CHD7; POU6F2; CBFA2T2; LDB1; ZNF33B; ZNF467; ZNF74; FOS; IFI16; FEZF2; ZNF93; HES1; HIC2; BARX1; FOXO1; TP63; HLX; SIX3; ELF5; TDP2; KLF7; NR2F1; CREB1; E2F8; TRPS1; ZNF266; OVOL2; SATB2; SMAD7; TFAP2C; ELF4; ST18; KDM5D; SOX2; PAX5; ZNF232; TRIM29; BNC2; INSR; MECOM; MYBL1; OSR2; ZFPM2; ZIC1; ZNF117; NFATC4; SNAI2; BCL11A; NEUROD1; GLI2; E2F2; ID1