Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10716	Dabrafenib	GSE70138	HA1E	Human	24h	0.37uM	EID0113

Response Information :

Types	Number	Response transcription factors
Up-regulation	45	VGLL4; HOXB2; RBFOX2; ATF4; CBX6; HOXB6; ERG; HOXD1; KMT2A; PHF20; IRF1; AHR; MED6; MYCBP; CLOCK; SMAD1; ZSCAN31; DDIT3; TGFB1; TWIST1; CDYL; TFAP2A; ZNF430; MTA1; NR2F2; FLNA; MEIS1; HLX; CEBPB; FOXJ3; LITAF; KLF9; PEG3; TXNIP; ISL1; ETS2; HMGA1; HHEX; ZNF589; ELF3; MECOM; HOXB7; CREG1; ZIC1; TRIB3
Down-regulation	72	CCNA2; SATB2; SMARCD3; CHD7; CDK2; TULP4; FOSB; TCF7L1; THAP11; KLF4; OLIG2; SSX1; ATF6; HEY2; TLE4; ABL1; HOXA11; REPIN1; YWHAB; PBXIP1; RARA; MYB; SMAD7; SALL1; MAF; ZNF107; NR3C2; ZNF443; NRBF2; MLXIP; AEBP1; NCOA4; POU2AF1; CTR9; ZNF667; HOXA10; FOXN3; CREB3L1; ZSCAN18; WNT4; TBX3; ZNF281; FOS; EMX2; CALR; IKBKAP; BACH2; ZBTB16; ZMIZ1; HOXC6; FOSL2; MSX1; MED24; NR2F6; NR1H2; TGFB1I1; CRY1; SNAI2; EDF1; IRF6; ZNF415; GATA6; LMCD1; HOXC10; OSR2; CBFA2T3; LEF1; DACH1; ZNF274; KDM5D; E2F2; GLI2