Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10626	Saracatinib	GSE70138	HA1E	Human	24h	3.33uM	EID0113

Response Information :

Types	Number	Response transcription factors
Up-regulation	91	ZNF410; RBBP8; GATA3; VGLL4; COPS5; MDM4; TCERG1; NRIP1; PATZ1; SAP130; YEATS2; ORC2; CSDE1; MSX1; RLF; HOXB6; PRKDC; SFMBT1; SNW1; FOXJ3; CTNNB1; ZMYND8; RBBP4; ZNF281; NCOA2; ZMYM2; TBL1XR1; KDM4C; XRCC6; ERCC3; ZNF217; CNBP; NR2C1; FUBP1; GATAD2A; NFYC; RNF4; ZBTB11; BRD2; UBE3A; JARID2; PHF20; AATF; ARNTL; CHD7; DMTF1; ZNF131; ELF1; CHD1; CITED1; ERBB2; HMGA1; DNAJC2; HDAC1; RORA; MLX; MTA1; CTR9; HOXC6; REPIN1; HMGA2; FOSL1; BRD4; SPEN; HOXB2; KAT6B; MTDH; TGIF1; PCGF2; TBL1X; LEF1; BAZ1A; SMAD1; MED1; CBX6; NFIB; NR2F1; ETS1; MYBL1; CBX3; ZHX2; NFE2L2; HNRNPD; HOXB7; BMI1; WT1; ESR1; HTATIP2; SOX9; CREB1; KDM5D
Down-regulation	135	NR4A1; BLZF1; MXD4; FOXF1; ATF6; PITX2; IRF9; PSMC3; HMG20B; JUNB; TFAP2C; ZNF112; ZNF200; TCEA2; POU2AF1; PHIP; MEOX2; MED7; ARRB1; TLX3; ZNF512B; WNT4; AES; ZNF175; MAPK8IP1; NKX2-1; EHF; SOX10; TRIP11; ZNF426; SKI; TXNIP; ETS2; ID4; ZNF443; PNRC1; GATA6; NFKBIA; PRRX2; CREBL2; MED12; RUNX1; SKIL; ZNF350; DLX2; TAL1; SIRT2; ZKSCAN1; BRCA2; EGR2; PTRF; RNF141; ZNF32; SHOX2; PAWR; BCL11A; NKX2-2; ZNF557; CUX2; PITX1; NAB1; ZNF79; MYRF; BARX1; NCOA4; TCF7L2; TCF21; BRIP1; EGR3; EPAS1; ZNF302; WWTR1; STAT1; ABL1; ISL1; SMARCA1; ASCL1; ZBED1; CCNC; MEIS1; TP53; CBX4; LYL1; ZNF345; VPS72; LITAF; ID1; PROX1; ELF5; ZNF623; ATF3; ELF3; KLF4; TLE4; NFE2; SNAI2; CBFA2T2; ST18; MEIS2; HOXD1; TLE2; HOXB13; ZNF589; STAT3; CITED2; ZMIZ1; ZNF117; ZNF189; GATA2; ARID5B; HES1; NKX3-1; VGLL1; AHR; ZNF721; ZNF232; FOXF2; RBPMS; CTBP2; PBX1; KLF10; TFAP2A; IKBKAP; TOX3; PIR; CREB3L2; ZBTB20; CBFA2T3; CREG1; PEG3; GLI2; ZBTB18; MAGED1; NFATC4; OSR2