Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10562	Regorafenib	GSE70138	HA1E	Human	24h	1.11uM	EID0112

Response Information :

Types	Number	Response transcription factors
Up-regulation	89	CEBPZ; TBX2; GATA2; BCOR; CREB3L1; DNAJC2; NFATC3; KLF6; SMARCC2; PATZ1; TBL1X; CARHSP1; KDM5B; SMARCD1; NFIL3; JARID2; CRY1; PLAGL1; LITAF; ZNF146; RBPMS; ID3; ITGB3BP; CARM1; FOSB; MSX1; RHOA; LMCD1; NELFB; SOX4; ZFHX4; HMGN3; CHD9; BATF3; PCGF2; EZH2; TLE4; SATB1; PMS1; SPEN; KAT7; BMI1; LEF1; SIM2; PDLIM1; PIAS2; BIRC2; ERBB2; ATF7IP; PTTG1; ING3; CUX1; ZBTB38; AFF1; PBX3; IRF2; RFX5; ZNF302; IKBKAP; NR2F2; CREB1; TBX3; MED24; PUF60; ETS1; NKX3-1; SUV39H1; HOXA10; HOXC6; BASP1; JUNB; STAT3; CTBP2; POLR2A; CTR9; CREG1; SSX1; FOS; TCF7; TSC22D3; FOXD1; HTATIP2; ZEB2; SIAH2; MTA1; HOXC10; STAT1; EGR3; KDM5D
Down-regulation	152	PRRX1; ZBTB16; ZBTB7C; IFI16; ZBTB43; ZSCAN31; TLX3; SOX10; INSR; TCEA2; RFXAP; GTF3A; POU3F4; HOXD3; PCGF3; ZNF667; SOX17; HOXD1; CERS4; ZNF239; ID2; TGIF2; MED12; TCF7L2; SOX18; L3MBTL1; ZNF606; ZNF133; BRCA2; HOXB5; ZNF415; ZNF532; ERBB4; ZNF224; VGLL1; FOXO1; PAX6; ATF5; ZIC1; HIPK2; ILF2; NEUROD2; SUPT6H; PRDM10; TAL1; ZNF175; ATF6; MED20; TRIM24; TERF2; TOX4; TRPS1; HES1; NKX2-2; NFE2; FUBP1; TRIM29; MED13; PLAG1; NFE2L3; ZNF304; NEUROD1; MECP2; LYL1; ZNF551; ZNF33B; ZSCAN18; CCNH; NKX2-1; FEZF2; PSMC3; AHR; CUX2; WWTR1; PRDM2; ELF5; ESR1; RAD21; HSF1; FOXA2; BCL6; BHLHE40; TFAP2A; TCEA1; HMGA2; POLR3C; NR4A2; ZNF432; GATA4; TP63; ETS2; ERG; ZNF117; ZNF160; CITED2; ZNF264; MYRF; SCAND1; JUN; ARNTL2; PPARGC1A; HOXA1; SAP30; GATA6; ZNF91; HIPK3; HLF; IL16; ID1; CEBPD; RXRG; RB1; ZNF623; ZNF165; ZNF544; ZFPM2; ZBTB18; SMAD1; ZNF665; ARID5B; BRCA1; ZNF331; MDM2; FOXF2; ELF1; SMAD3; ADRB2; ZMIZ1; BCL11A; EHF; CNOT3; VPS72; ZNF573; AEBP1; PRKDC; ZNF140; MYBL1; ZNF232; NFAT5; MEIS2; NFIB; TP53; ELF3; PEG3; NR2F1; EMX2; HIRA; ATF3; NFATC4; NR2F6; SOX9; MNDA