Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10518	Alectinib	GSE70138	HA1E	Human	24h	0.04uM	EID0112

Response Information :

Types	Number	Response transcription factors
Up-regulation	163	NFKBIB; KDM5B; BRF2; ZBTB17; SHOX2; FOXJ2; BCOR; ZBTB48; PBXIP1; VGLL4; MKL1; GATAD2A; TAF5; STAT5A; ASH2L; SSBP3; ETV5; SPIB; IRX4; TULP2; CITED1; SUPT5H; HMGA1; RARB; THAP1; ARID3A; MED16; NR1I2; BRDT; FOSB; C1D; CIZ1; TRIM24; MED4; ARL2BP; KLF2; ARID3B; ZNF671; SRY; YWHAB; TFCP2; ZNF835; TDRD3; KLF12; ZNF44; SOX13; CALR; WWTR1; DLX4; ING1; KLF4; HOXC5; NFYC; PRRX1; ZNF141; PIR; ETV1; HIRA; ZBTB43; ZNF136; PRDM10; LPIN2; SOHLH2; ING4; ZNF611; CDK9; ZNF468; HMGB3; HOXC4; ETS1; ZNF329; MAFF; TCF7; SOX9; NR1H2; KAT6A; POU2F1; TFAP2C; ZNF701; TFCP2L1; FOXG1; ZBTB38; CRYM; MTDH; ZBTB16; IRF2; EGR4; SSX1; WWP1; NFATC1; ZNF512B; CARHSP1; EGR1; SIM2; THAP11; MYB; ZFHX3; NR5A2; GATA4; EPAS1; HMGA2; CBFA2T3; CREB3L2; TWIST1; SMARCB1; KDM5D; MXD1; CREB3L1; SUV39H1; SCAI; GATA6; MYT1L; NR4A1; IFI16; INSR; FOS; HIC2; BRCA1; TBL1X; HSF1; RCOR1; PARP1; TSC22D3; SUB1; TRIM29; ELF3; ATN1; KAT7; JUNB; ELF5; RNF141; ERBB2; MKL2; NFKB2; ZNF721; CREG1; PHF8; HEY1; JUND; REL; CREM; TLE4; SATB2; KDM5A; MTA1; SPDEF; TSC22D1; TRIM28; PTRF; ZEB2; CTR9; ZBTB18; TBX3; ARID1A; ASCL1; NKX3-1; ZNF264; BCL11A; HOXC6; NR1H3; NR2F1; EGR3; WT1
Down-regulation	131	RCOR3; ZNF195; KMT5A; ZNF3; ABL1; PBRM1; CCNA2; ID3; HOXA7; ZBTB1; BIRC2; HOXD3; ZNF516; TAF1D; ZNF23; HOXB5; TEAD1; PAXBP1; DEK; SCAND1; PSMD9; NKX2-2; ZMIZ1; HOXB3; ETS2; USP22; WWC1; HMGXB4; NFATC3; CBFA2T2; HOXA10; FLNA; MLXIP; ZMYM2; RBFOX2; TCF12; PEX2; TRAK1; RXRA; RNF4; PMS1; SMARCE1; CENPF; PAWR; TSC22D4; ZNF133; ZMYND8; RYBP; POU3F2; ZNF302; NR2C1; VEZF1; RNF10; HOXD10; MEIS1; ZBTB11; ELK3; PCGF3; NHLH2; GTF2IRD1; IRF7; HOXB7; TRIP6; SAP30; ZNF12; MECOM; KLF10; CEBPB; ID2; ZNF84; RBPJ; MYC; NCOR2; EMX2; FOXF2; ID1; ZIC1; SMAD3; STAT6; RORA; TFEB; MED17; ZBED2; ZNF32; DDIT3; HOXB6; ATF5; ZSCAN18; ZNF117; CERS6; SNAI2; CCNH; ARID4B; ENY2; PHF20; NFAT5; TFAP2A; EHF; ZNF43; RFX5; JARID2; ZNF232; SLC2A4RG; CDYL; BCL11B; PAX8; ARNTL2; HOXD1; OSR2; ZNF131; ZFPM2; TOX3; MYRF; CNBP; MYBL1; TOB1; ZNF91; SMARCD3; CTBP2; EED; BMI1; TAL1; SPEN; CREB1; SATB1; ATF4; NR2F6; NFE2L1; TULP3; INSM1; NFATC4