Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10516	Alectinib	GSE70138	HA1E	Human	24h	0.37uM	EID0112

Response Information :

Types	Number	Response transcription factors
Up-regulation	69	VGLL4; CARM1; GATAD2A; EN2; FOXM1; SOX17; BHLHE41; HOXB7; PLAGL1; EZH2; NEDD8; MSC; ZNF267; NCOA6; HMGN3; NELFB; ZNF589; HMGA2; ZBTB38; SUZ12; SAP30; TADA3; NFE2L3; ZNF32; SPEN; SP3; ZBTB16; ZMYND8; BATF3; UBP1; CBX3; IKBKAP; HTATIP2; NR2F2; BRD8; ERBB2; DLX2; NAB1; LMCD1; NFIB; MYCBP; TLE4; HOXA10; ARID4B; SOX9; MSX1; SUV39H1; ENO1; MYRF; STAT1; IRF4; GATA6; ZFP36L1; FOS; FOXG1; ID2; TRIM16; BMI1; TSC22D1; SIAH2; ELF3; MAGED1; ZBTB18; MTA1; NR2F6; EGR1; WT1; SSX1; RUNX3
Down-regulation	118	ZNF692; ZBTB48; PBXIP1; CHD3; BACH2; SPI1; L3MBTL1; CALR; IRF3; HDAC5; KAT2A; DNMT3B; NR4A3; ZNF331; RRN3; SUPT3H; CBX4; CD3D; ZNF532; MECP2; TFDP2; MED12; ZNF721; RARG; ATF1; LEF1; FOXF2; MED14; DBP; ZNF224; MDM2; ATF6; HHEX; SSBP2; NR4A2; ASCL1; TEAD1; HIVEP2; BBX; ZNF160; IL16; EYA1; TAF1; HLX; CDK9; KLF7; ZNF623; SMAD4; ZNF573; RB1; SHOX2; ZFHX3; ZNF587; ZNF669; ESR1; KLF3; HES1; KLF13; REL; SMARCA1; PRRX2; NR4A1; CBFA2T2; TCF7; NFIC; ATN1; SOX10; HDAC6; CREM; CUX2; JUP; TBX3; NFE2; BCL11B; TWIST1; FUBP1; LYL1; HOXA1; FOXF1; INSR; NCOA3; TCFL5; ID3; HMBOX1; PITX1; SALL2; SNAI2; CEBPD; NFAT5; CITED2; MECOM; TFAP2C; NFATC4; MEF2C; ZNF44; BCL11A; ISL1; PPARD; TP63; NR1H2; VPS72; HOXD1; RFX5; SOX2; ID1; NKX2-1; ZIC1; ZNF652; ATF3; ARID5B; AHR; SATB1; PEG3; ZNF264; TOB1; NFE2L1; CEBPA; ZNF423