Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10513	Alectinib	GSE70138	HA1E	Human	24h	10uM	EID0112

Response Information :

Types	Number	Response transcription factors
Up-regulation	64	FOSL1; DDIT3; STAT1; CCDC59; DNAJC2; IRF1; ZBTB11; BHLHE41; BIRC2; TAF9; RNF6; HMGA2; ZMYND8; GMNN; ZMYM2; NFKB1; TBP; ZNF410; ATF4; CEBPG; MYC; IFI16; BBX; COPS5; HMGA1; SP100; GATAD2A; SNW1; MED1; NONO; HDAC9; BCL10; MTDH; PCGF1; ING2; CHD1; RREB1; HNRNPD; CEBPB; MITF; COPS2; CREB1; ZNF266; TRIP6; TCEA1; CRY1; PUF60; RBM39; IKBKAP; PIR; CREG1; ZNF91; CTBP2; SP140L; TRIM22; CNBP; ZFP36L1; SMAD1; SPEN; TLE1; NFE2L1; EMX2; ARID5B; KDM5D
Down-regulation	125	GTF2A2; PBXIP1; AES; MYBL2; BRWD1; ARHGAP35; TGFB1I1; MYCN; SLC2A4RG; CALR; THAP7; CUX1; LMCD1; FOXO1; CDK2; FOXF1; GRHL2; PAWR; CREBZF; ID2; SMARCA1; MXD4; GLI2; FHL2; E2F8; ZNF141; DLX5; ZNF444; HOXC4; HSBP1; FOXC1; TCF7L1; GATA6; LITAF; ZSCAN16; ZBED1; NFIB; HMG20B; SOX4; ZSCAN31; MYRF; SMAD6; KLF2; WNT4; NR5A2; SMAD7; NEDD8; ID1; ZBTB44; ZNF226; PRRX1; RBL2; FOXO3; OLIG2; ID4; HOXA10; ZNF124; NR3C2; ZNF165; TXNIP; DLX2; HOXA1; HOXC10; ZNF22; NLK; MYCBP; SMARCD3; CENPF; HDAC6; TFCP2L1; OSR2; HES1; ZNF711; PARP1; MEIS1; BHLHE40; SPIB; ZNF587; CARHSP1; NFATC1; NR2F1; ELF3; SMAD3; ID3; ASCL1; TCF4; TCFL5; MLLT10; AEBP1; TSC22D3; SATB1; HMGB3; DMTF1; NFAT5; RBPMS; PKNOX1; NR1H3; FLNA; PBX1; CCNH; IL16; NR4A2; CNOT3; SKI; TOX3; ELF1; BCL3; GFI1; LEF1; IKZF1; BCL6; HMGB1; TRPS1; KAT6B; MEIS2; CBFA2T3; NR3C1; EGR1; ZBTB18; MYBL1; TBX3; BCL11A; NR2F2; HOXC6; ZNF274