Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10493	Vx-745	GSE70138	HA1E	Human	24h	0.12uM	EID0112

Response Information :

Types	Number	Response transcription factors
Up-regulation	89	WWTR1; ZNF593; BHLHE41; CBX3; HNRNPD; SMARCE1; TBP; ZMYM2; MTDH; NFKBIA; ZBTB11; ING2; FOXM1; MAFF; TFDP1; TAF9B; SNW1; RNF138; DNAJC2; SAP30; COPS5; HMGB2; FOXJ3; DR1; BCLAF1; CREB5; MED1; TSC22D2; ZFHX4; MYCBP; SMAD3; NPAS2; IRF7; ATF4; TEAD4; RYBP; DEK; PIAS2; VEZF1; REST; GATAD2A; PSMC3IP; DDIT3; ERBB2; CREB3; MBD2; KLF10; CCNC; CENPF; FLNA; FOXO3; GABPB1; ETV5; SUB1; BMI1; CRY1; SATB2; SMAD1; SNAI2; HLTF; ELK3; SFPQ; MAFB; NR1H2; NAB1; EDF1; NFE2L1; CNBP; TCEA1; ZNF131; TOB1; ZNF12; PBX3; CEBPG; CBFB; KLF5; TLE1; ZFP36L1; FOXD1; TULP3; NFIB; PTRF; ATF3; RFX5; PBX1; EMX2; TOX3; NKX3-1; HOXC6
Down-regulation	217	TERF2; SNAI1; ZBED1; DLX4; SMAD7; KDM5C; IRX4; ZNF254; HLX; ZNF574; PAX9; NKRF; ZNF444; SSBP3; ZNF701; TFAP4; ZKSCAN3; EMX1; ZNF225; TBX21; FLI1; MZF1; TLE2; MLXIPL; MBD3; NKX2-1; STAT4; TFEB; ZKSCAN1; ZSCAN31; ZSCAN18; ZNF85; HMGXB3; NEUROD1; ZNF141; CDX2; PRDM1; BCL11A; ZNF329; RARG; CIC; HMX1; MBD4; ZNF253; ELF3; FOXF2; PRDM2; CERS4; NR0B1; NR5A2; TAF1C; ZBTB44; POU2AF1; RARB; MEN1; FOXI1; SSBP2; FOXA2; CHD2; BACH2; SOX10; WHSC1L1; MDM4; WNT4; ZNF671; ZNF506; CBFA2T3; ZNF117; HBP1; NLK; PAX5; ZNF557; CREM; AR; GRHL2; ZNF692; LZTR1; E2F4; ZKSCAN4; HIPK2; NFE2L2; HABP4; TGFB1; SETDB1; ARID3A; BARX1; TRIM24; NHLH1; CSDC2; TCF25; RSF1; CBX7; SPIB; NR4A2; PNRC1; DLX5; MEIS2; ZNF286A; ZNF778; POU2F1; BRWD1; ZNF107; ARID5A; REL; SKI; THRA; ACTL6B; TBX2; CUX1; ST18; PIAS1; CALR; PPARD; ZNF611; MDM2; VGLL1; TAF1; CALCOCO1; ZNF165; KMT2A; CNOT3; LYL1; ZNF43; SMARCB1; LITAF; SCAI; TCEA2; TCF7; IRF9; ZNF124; ZNF529; SALL2; ZNF552; ZNF721; MLXIP; MAP3K10; ZNF219; TDP2; NFAT5; MED14; ZNF500; BAZ1B; RBL2; CBX6; ZNF160; OLIG2; ATN1; KLF13; CBFA2T2; SPDEF; TRIM16; MYCN; NFATC1; NKX2-2; ERBB4; HMGB1; CHD8; EPAS1; IRF6; IRF8; FOXF1; ZIC3; ZBTB16; JUP; MTA1; NFE2; ZNF587; ZNF544; CITED2; ID1; ZNF331; ZNF264; CIITA; ASCL1; ZNF665; MYT1L; SOX2; CRYM; FOXO1; ARID1A; INSR; SATB1; NR2F1; AEBP1; IL16; BCL6; ADNP; TP63; FOXL2; TTF2; FOXA1; HOXC10; NR4A1; E2F2; GATA6; GFI1; MYB; GATA3; ETV1; SSX1; DMTF1; IKZF1; ZBTB20; RUNX3; FOXG1; CEBPA; VPS72; ZFPM2; TSC22D3; RELB; MYBL1; HEY1; ZNF274; FOS; NR1H3; NR3C1; EGR1