Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10488	Dabrafenib	GSE70138	HA1E	Human	24h	0.04uM	EID0112

Response Information :

Types	Number	Response transcription factors
Up-regulation	109	BTAF1; TGIF1; E2F3; PRKDC; PMS1; AES; TBX1; MGA; NCOA2; ST18; E2F8; MED14; PHIP; TAF1D; SSBP2; ATF3; PRDM10; FOXF2; ZZZ3; HES1; MED20; TCEA1; NR4A2; COPS5; TAF11; NR2F6; ZNF536; ZNF532; DYRK1B; TSG101; AHR; TDP2; TCF3; EPAS1; TGIF2; TFDP1; TRIM22; PSMC3; TULP4; SOX13; NR1I2; FOXF1; AGO2; NFX1; CBFA2T2; ZMIZ1; PGR; ZNF623; ZNF84; SUPT3H; PEX2; SMARCA1; ZNF217; SUMO1; HSBP1; NR2C1; HSF1; ZNF124; HLTF; POU5F1B; NKX2-2; SFPQ; CCNH; RREB1; TOB1; ZNF7; ZNF415; DEK; TFAP2A; SATB2; NFATC4; ID3; MXI1; ZEB1; ZSCAN18; HOXD1; STAT1; HIPK1; CALR; DAXX; CSDE1; ZNF232; TP53; ID1; MYRF; PBX1; DMTF1; ZNF331; FUBP1; NR1D2; LIN28A; SKI; DACH1; TAL1; ARNT2; ATF5; CNBP; HMBOX1; DDIT3; INSM1; ZFP36L1; ZNF573; NFE2L1; ESR1; IFI16; BHLHE41; PEG3; HIRA; ARID5B
Down-regulation	101	ZMIZ2; MED21; BASP1; UBE2I; FHL2; EN2; PCBD1; RYBP; ZNF384; SIRT7; NELFB; NEDD8; ZBTB24; HMG20B; ARID5A; EZH2; RHOA; SIAH2; FLNA; BCL6; CHD8; HOXC10; LMCD1; MLXIP; NCOR2; ESRRG; FOXO3; DRAP1; TFCP2L1; NR2F2; ZBTB18; PLAGL1; CREG1; RBPMS; HMGN3; RORA; CRY1; ING2; FOSL2; TBL1X; ATF7IP; POU2AF1; CHD9; STAT6; TAF10; MED1; CUX1; ZNF22; KLF6; MED24; FOXC1; MAFB; WWC1; KLF5; YBX1; MTA1; BHLHE40; TRIM28; KDM5D; CTNNB1; TCF7L1; NFIB; SLC2A4RG; SUB1; ID2; SMARCD3; BCL3; KLF2; KLF4; SUV39H1; SSX1; INSR; ERBB2; POLR2A; REPIN1; ZBED2; CRYM; MECOM; ID4; NKX3-1; ZNF274; PCGF2; TSC22D3; KDM5A; STAT5B; ARID1A; IRF4; MEOX2; TRIP6; NFAT5; SATB1; GATA3; WT1; MYB; MYCL; CEBPA; NR3C1; EGR1; ZEB2; HOXC6; RUNX3