Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10484	Dabrafenib	GSE70138	HA1E	Human	24h	3.33uM	EID0112

Response Information :

Types	Number	Response transcription factors
Up-regulation	64	KAT8; AES; C1QBP; HDAC6; NCOA2; COPS5; YEATS4; ZNF33B; TCF7L2; TRIM29; BCOR; TERF1; USP21; TAF12; GMNN; HIVEP1; OSR2; PQBP1; CTBP2; RBBP8; EHMT2; BCLAF1; PAX8; TGIF1; ZNF532; SMARCB1; RBFOX2; ETS1; CDK9; BBX; NHLH2; ZFPM2; CREB1; TULP4; HDAC9; USP16; MYBL1; CRY1; COPS2; SMAD3; TFAP2A; ZHX2; RREB1; SMAD4; PITX1; HOXD1; TCEA1; SAP30; ST18; TP63; DAXX; CREB3L2; MEIS1; RBPJ; HMGB3; NR2F1; YBX3; ZNF652; ZFP36L2; ARID5B; HIRA; EMX2; ZNF423; PBX1
Down-regulation	91	ARNT2; CDK8; OVOL2; SATB2; ZHX3; SOX9; TSC22D2; EGR2; RBBP7; NR1I2; ZNF267; TCERG1; EGR3; RNF14; DLX2; ASCL1; ZBTB43; BCL10; WWTR1; CARM1; TFEC; GATA6; STAT6; TFCP2L1; ZKSCAN1; ELF5; OLIG2; SIM2; PPARD; RCOR1; ARID4A; CCNT1; IRF8; SP110; PHF20; FOSL2; BATF3; NKX2-2; MITF; ZNF552; FOXF1; HLX; ZNF587; MTA1; FOXO3; ZNF500; ZNF200; STAT3; CDIP1; TAF7; MYB; XBP1; CREB3L1; SUZ12; FOXD1; PLAGL1; HMGA1; TOX3; YBX1; ZBTB18; NFAT5; ATF5; MECOM; SOX11; TXNIP; ENO1; SCAND1; FLNA; HEY1; SATB1; NCOA4; ZBTB38; GATA4; TRIM16; ID4; PTTG1; RUNX3; NFIB; KLF10; SIAH2; CREG1; PURA; SUB1; STAT5B; KAT6B; ZBTB20; GATA3; MAGED1; NKX3-1; HOXC6; ZNF274