Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10392	Azd-7762	GSE70138	HA1E	Human	24h	10uM	EID0112

Response Information :

Types	Number	Response transcription factors
Up-regulation	163	HMGN3; VGLL4; DNAJC2; SND1; TXNIP; ZNF675; BCOR; ZNF254; NCOR2; ZNF107; MSX1; CREB3L1; NR0B1; DDX54; NKX2-1; ZNF267; ZNF571; WDHD1; ZNF468; TRIM32; MXD4; ZNF226; MAGED1; ZNF492; TTF1; TSG101; TOX; E2F5; HOXB7; KDM5B; ELF5; CREB1; ARID4A; SKI; PTTG1; ZNF813; JARID2; MED21; ZNF225; ZNF764; RNF14; TRIM24; KLF12; TCF4; DNMT3B; TFEC; KAT6B; ZBTB39; ING3; ECD; SSX1; MITF; HBP1; HTATIP2; RBPJ; HMGA2; SMAD2; HLTF; ING1; ZNF14; ZNF184; ZNF711; NFYC; HSBP1; BRCA1; RBL2; AFF1; CEBPA; IKZF3; ZNF43; THAP1; JUNB; ZNF227; TGS1; NFIL3; FOXN3; BRD3; ZNF124; TEAD1; HOXB6; ID3; NEDD8; PDLIM1; CNOT2; XBP1; TSC22D3; PRDM13; RCOR1; SUV39H1; KDM5D; RXRA; GATA6; HMG20B; TERF1; SHOX2; DRAP1; SFPQ; TSC22D1; KAT7; ARID4B; EGR2; HIC2; BAZ1A; ENO1; ITGB3BP; HSF2; SMARCA4; MYCBP; PLAGL1; BLM; NR1D2; PARP1; TBPL1; MED1; EZH2; RHOA; EGR1; CRK; NFATC1; NLK; ID2; BCL3; SUB1; CCNE1; BACH1; LIN28A; RNF141; FOXL2; ZBTB38; ZNF117; NR2F1; DMTF1; LMCD1; MTA1; SP140; PCGF2; ADNP; NFE2L2; PSMD9; KDM5A; PURA; TFAP2C; FOS; RBPMS; RBM14; FOXA1; SMARCA2; PKNOX1; TOB1; HDAC4; PHF8; BASP1; REPIN1; CTR9; PAX5; SPDEF; IKBKAP; IKZF1; ZFPM2; ZEB2; EGR3; HOXC6; WT1
Down-regulation	178	CDK2; EZH1; EYA1; TRIM29; CAPN15; MECP2; ZKSCAN1; LHX1; RELA; BHLHE40; ZNF76; TOX4; MBD1; ZNF500; HIF1A; ZNF202; KMT2A; ILF2; CCNH; IFNB1; HINFP; UBE3A; CAMTA1; MED12; CRTC1; RARA; MMS19; MXD3; TCF12; TGIF2; PNRC1; RXRB; ATF2; MED15; THAP4; CDC5L; RXRG; RING1; MAFF; RFXANK; BRD4; MECOM; SMARCC2; IRF1; BCL11A; NPAS2; ZHX2; HSF1; FUBP1; RAD21; EWSR1; MYCL; CHD8; GMEB1; PBRM1; ETV7; ZNF91; FLI1; ZNF423; ARID5B; RBFOX2; ZNF177; RORA; ZNF12; SUPT6H; POLR3C; CTBP2; HIRA; MEIS1; MEIS2; CCNA2; NCOR1; ZNF160; STAT1; NFKB1; ARNTL2; COPS2; RBM39; SCAND1; SMAD4; TULP3; SSBP2; RNF111; PSMC3; EPAS1; PRDM2; DLX2; HIPK2; TP63; CBFA2T2; ENY2; BHLHE41; SMARCB1; CUX2; RYBP; PCGF3; ZZZ3; VPS72; MAP3K10; KLF1; TAL1; PRRX2; CALCOCO1; HOXB5; ST18; IRF9; NFKB2; IRF7; APEX1; COPS5; SNAI2; GTF2IRD1; AHR; STAT4; TDP2; YAP1; TP53; RFX5; ISL1; HOXD1; MED17; ZNF573; CHD9; ZNF467; ZMIZ1; SUPT3H; HOXB2; CERS6; EED; RB1; FOXF2; ZNF721; JUN; NFATC4; CBX3; SIRT2; CCNC; ESR1; LDB1; CHD7; KLF13; NFIC; ATF5; YBX3; ZNF623; ATF3; KLF7; ZNF266; HMBOX1; SMARCA1; KLF6; DDIT3; DEK; SALL2; ZNF140; SOX17; ZFHX4; MEOX1; ZFP36L1; PRKDC; ZEB1; ACTL6A; HMGB1; SMAD1; DACH1; CITED2; ZBTB18; CRYM; ZNF331; ERG; NR2F6; ERBB4; PEG3; ZNF232; ID4; INSM1; SOX9; PBX3