Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID10350 Belinostat GSE70138 HA1E Human 24h 3.33uM EID0078
Types Number Response transcription factors
Up-regulation 81 TGFB1; FOXO4; NFIL3; HOXA10; CEBPB; MXI1; VGLL4; TCF7L2; ETV5; HDAC9; HOXA5; SPIB; OSR2; IRF3; WWC1; ZNF281; CREM; ARID1A; ZNF354A; KDM4C; HEY2; PIAS1; RUVBL2; TCEA2; CBX4; ZNF331; EP300; ZKSCAN1; SOX9; JUND; MITF; BRD4; RLF; BCL3; SOX13; ATF3; CCNH; AHR; MKL2; TSC22D1; SPEN; ARID5B; TOB1; TCEB2; ZNF415; CERS6; JUNB; RSF1; MAF; IRF8; ZNF654; BACH2; SOX4; ZNF443; ELF3; NR4A2; FOXO1; RUNX3; HHEX; ZNF544; BTG1; HEY1; BCL11B; INSR; SMAD1; MEIS1; PAX5; GATA6; ZFP36L2; CITED2; ZBTB18; TLE1; NFE2L2; ZFP36L1; ZNF91; ARNT2; NR2F2; HOXB2; SOX11; TRIB3; WT1
Down-regulation 72 NFKBIA; XBP1; TFDP1; FOSL1; ATF6; ABL1; PCBD1; FOXM1; PAX8; UBE3A; PRMT2; DDX17; DDX5; CNBP; PBRM1; BACH1; STAT6; BASP1; RELB; DMTF1; BCLAF1; KLF4; PHF2; RBM39; FOXL2; TGFB1I1; NKX3-1; REPIN1; NFYC; CCDC59; NCOA4; TRIM29; PITX2; ATF1; HDGF; TCF12; NFKB1; GATA4; TP63; MED1; ATF4; IRF5; RBM14; TLE4; ING3; HNRNPD; RXRA; ZBTB38; SLC2A4RG; SMARCA1; BAZ1A; HMGB2; HOXB7; EDF1; LMCD1; KAT6B; SFPQ; NCOR2; NUP62; RFX5; SSX1; HMGB3; PDLIM1; HOXC6; SUV39H1; ZEB2; ID1; KDM5D; MAFB; CREB1; PBX3; TP53