Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID10228 Cgp-60474 GSE70138 HA1E Human 24h 3.33uM EID0078
Types Number Response transcription factors
Up-regulation 645 IKZF1; EGR1; TAF1C; ZNF671; RFX1; ZNF816; HOXC8; TAF1; ZKSCAN4; NKX2-5; GLI2; FOXF1; BCL11A; ZBTB44; SSBP3; SOX5; THRA; CDX1; NR6A1; HNF1A; TRPS1; WHSC1L1; KMT2D; ZNF264; EP300; TLX1; HNF4A; ARID3A; TLX2; ZNF154; GLI3; ASH1L; ZNF75D; HOXC5; LMX1B; PRDM16; ZFHX2; VGLL1; NHLH1; MECP2; HIF3A; PAX7; NFKBIB; OVOL2; FOXF2; ATOH1; ZNF117; KLF13; NFATC1; ZNF3; ZNF778; ZNF34; UBTF; ONECUT1; ZNF500; GATA2; CARF; HAND2; HMBOX1; REL; NFATC4; SOX3; AFF2; AR; PAX1; MTA2; OLIG2; MNX1; ZNF701; PRDM2; SOX2; ZNF235; NKX3-2; CHD2; SALL2; ZSCAN2; RBPJL; TONSL; HEYL; CBFA2T3; MYCL; ONECUT2; RARG; PRDM14; TFAP4; NEUROD2; HDAC11; HDAC9; DLX6; ZNF345; ALX4; FOXH1; CIITA; IKZF2; MAML3; HSF4; FOXP3; ZNF835; DLX5; ZNF253; SOX21; TULP1; NR5A1; TAF6L; ZNF331; ZIM2; NEUROD4; CEBPE; PROP1; ZNF250; ZNF507; ZNF688; ZNF304; NFIC; PRDM1; NFAT5; ZNF536; ZSCAN18; FOXJ1; SRCAP; ZNF695; IRF6; ATF7; BRWD1; RFXAP; HIPK2; CCNT1; ASCL3; ATF6; HOXC4; RFX3; DLX2; NAB2; HNF4G; SOHLH2; PRDM8; ZNF623; ZNF224; EMX1; ZNF415; THRAP3; GRHL2; ALX3; PAX3; NEUROD6; ZNF556; NEUROD1; ZNF93; ZBTB7B; GBX1; POU6F1; EHMT2; BARX1; ZNF221; NR0B2; WNT4; GFI1; MYT1; NPAS1; ZKSCAN3; RBL2; ST18; FOSB; ZNF350; NR5A2; LHX2; ZNF174; SMAD9; HESX1; ZKSCAN1; HMX1; ZNF696; SOX18; HOXB5; PRDM9; ZNF573; STAT2; ZNF814; TP73; ZNF562; CBX8; TRIM25; LDB1; GMNN; CDX2; RXRB; TULP2; HOXB1; HOXA3; CHD9; TCF21; ZNF768; MED12; GLI1; LHX5; ZNF654; LZTR1; ESR2; ATF6B; ZNF665; TBX19; TFDP3; MLLT1; MYNN; AIRE; NEUROG2; MAPK8IP1; NR2E1; ETV7; ACTL6B; ZNF33B; SNAI1; HNF1B; NFX1; ZNF467; PDX1; NFIX; E4F1; ZFP2; EZH1; CDX4; IKZF4; CNOT3; RSF1; TBX6; KLF7; SIX6; SNAI2; ZNF211; SPDEF; TUB; ZIC3; SPIB; ZNF324B; ARL2BP; ZBTB48; MED25; HOXC13; SHOX; E2F4; ETV3; CIR1; LHX3; BARX2; ZNF136; TFAP2A; ZNF667; JUP; ZNF611; CBX2; NKX2-2; HOXA6; ZNF141; THRB; ZNF606; ZNF195; PRMT2; POU3F4; TBX10; TBX5; POU3F3; ZNF175; GBX2; CBX7; ZNF16; POU6F2; BNC1; NR1I3; CAMTA2; VENTX; SIX5; ETV6; MAP3K10; YBX2; ING4; PPARG; CALCOCO1; HINFP; RAX; INSM1; RORB; GATA1; FOXA2; ZNF286A; FOXE3; ZSCAN9; GRIP1; ZNF205; EVX1; MEIS1; ZNF219; ZNF160; RFX2; CBX6; PRDM12; DCC; POU3F2; SCRT1; ZNF440; HES2; FUBP1; E2F5; HIRA; NKX6-1; NCOA3; SRY; SUPT3H; KDM5B; LMO1; HOXB8; ZNF107; TBX4; ZNF132; ZNF7; TAF4B; NEUROG1; NEUROG3; SKI; SOX1; TBX21; KAT2B; VPS72; ZNF343; PKNOX2; ZBTB39; PRDM5; ZNF550; TAF5L; MAK; IRF8; ZSCAN32; DYRK1B; ZNF74; NR0B1; ZBTB3; PROX1; ZNF682; ZSCAN31; KLF15; HOXC11; GON4L; ZBTB16; ZNF281; TWIST1; RORC; CD3D; OVOL1; PITX3; TCF7; ZNF510; ZNF239; HDAC5; NFKB2; VSX1; HHEX; DOT1L; MBD4; ZNF124; CRTC1; ZNF771; ETV2; EPAS1; FLI1; TOB1; MYRF; ZIC4; ZXDC; ESRRB; NR1H3; SSX7; HEY1; ZNF551; ZNF225; ZEB1; CBX4; DLX4; INSR; FOXB1; NHLH2; MKL2; ZNF273; TBX1; ZNF44; ATF3; PRDM13; CREBL2; TEF; ZNF223; ZNF282; TULP3; HSF1; TBR1; HOXD13; MZF1; ZNF14; PAX6; ZNF180; LHX6; POU2F2; PPARA; ESR1; EN2; TXNIP; ZNF423; ZNF444; TRIM33; ZNF79; POU2F3; ZNF142; MED15; HLX; HAND1; ZNF710; SOX14; LYL1; PPARD; NR2C1; ZNF506; FEZF2; HDAC4; PHOX2B; ZNF140; TCF7L2; PEG3; HIVEP3; CCNH; ZNF10; ZFP30; NKX2-1; CHD4; ZNF257; CBL; ELK4; SOX17; TGIF2; BRDT; TDP2; SPI1; NR1I2; RCOR3; CRX; ZNF215; ZNF549; L3MBTL1; MLLT10; CDIP1; ZNF544; ZNF41; ZKSCAN8; TBX3; PRRX1; ZNF586; FOXA1; ERBB4; ATN1; ZFY; ZFPM2; ZNF711; CREM; FOXD3; FOS; TRIM24; ZNF362; EP400; PLAG1; ZFHX3; CEBPA; AEBP1; GSC2; ZNF528; SMARCD1; BRF2; CREBZF; ZNF442; ZNF324; PAXBP1; NR4A2; VDR; TFDP2; ZNF391; SCMH1; HOXB13; SATB2; ZNF35; HOXD3; FOXN1; CALR; DBP; HOXD12; IKZF3; SREBF2; CTNNB1; SCAI; MED14; BRD2; ARID5A; CERS6; TRAK1; ZBED2; PBXIP1; ZNF669; ZNF287; FOXO4; CRYM; PRDM10; CEBPD; SNAPC4; TERF2; TCF4; SOX13; ZNF80; ZNF587; ZMYND8; CUX2; ZNF43; TOX4; ZHX3; PFDN5; IRF1; ZNF85; LITAF; ZNF721; NOCT; SETDB1; ZNF552; KLF9; MLXIP; GCFC2; ZBTB20; ISL1; TCEA2; TLX3; ZNF652; MYCN; ZNF529; PHOX2A; ZNF764; KDM4C; ZNF200; RING1; TP63; FOXI1; PBX2; ZNF254; ZNF493; ZNF749; VHL; GTF2I; TAF1D; TFCP2; ZNF589; SOX12; MDM2; TAL1; SIX3; PHIP; ZNF407; ZNF131; PAX5; TGFB1; MXD4; ZNF24; GCM2; IRF5; RFX7; NR4A3; BNC2; PAX4; ZNF329; CBFA2T2; MXI1; ZNF557; DMTF1; MDM4; ZIC1; PEX2; ZNF177; NR4A1; SMARCB1; ZNF443; ZNF532; ZNF492; ZNF83; EHF; TAF9B; NLK; CUX1; IRX4; MEIS2; FOXG1; ZNF248; BAZ2A; TFEC; POLR3C; TTF2; HOXB6; HOXD1; BACH2; ATF5; TCEB2; RORA; MEF2C; PGR; STAT4; ZNF91; NR2F1; SMAD6; SATB1; JUN; BRD4; NR3C2; CNOT2; HIPK1; CITED1; JAK2; LIN28A; E2F2; ETV5; MECOM; IRX5; TOX; ASCL1; PBX1; ID1; HIC2; PURA; WT1; ELF4; EN1; CREB1; BHLHE41; OSR2; TOX3; ID3; TRIB3; SSBP2; PITX1; TCFL5; MYBL1; ARNT2; NFE2L2; DACH1; HOXB2; LEF1; NFATC3
Down-regulation 177 FHL2; HOXA10; HDAC2; XBP1; GTF2A2; CRK; ABL1; PUF60; BASP1; PAX8; HNRNPD; USP22; SCAND1; EZH2; NFKBIA; FOSL1; MYC; ECD; ATF4; UBE2I; NRBF2; MED6; CEBPZ; APEX1; NFIL3; NELFB; NUP62; CCNC; TRIP6; CCDC59; GATAD2A; ENO1; CCNA2; DNAJC2; PCGF2; PREB; RNF4; TAF11; HOXA11; HMG20B; VEZF1; SNW1; BCLAF1; TTF1; CBX3; FOXC1; BHLHE40; ITGB3BP; CBFB; SMARCE1; SAP30; NKX3-1; EDF1; NCOA4; RBPJ; CENPF; PSIP1; XRCC6; BIRC2; CRY1; RBM14; FOXO3; AFF1; CDK7; TBL1X; TEAD4; SFPQ; FOSL2; DDX5; SIRT7; RAN; NR2F2; ZNF146; TRIM28; DNMT3B; VGLL4; BRD8; TAF7; FLNA; SETD2; NONO; TCF12; ZFP36L1; ID2; WDHD1; CTBP1; AATF; ELK3; DR1; NPM1; REXO4; SMAD2; JARID2; HOXC6; BMI1; YWHAB; WWC1; ELF5; TRIM32; MBD2; RBPMS; UBE2B; CEBPB; FOXK2; NCOA6; THAP1; TRIM16; KAT7; BRD3; SND1; RBL1; PMF1; ELK1; LMCD1; FOXM1; SMARCA5; LPIN2; NR1H2; RUVBL2; IFI16; MAGED1; PQBP1; SUB1; JUND; PDLIM1; MED24; YBX1; RARA; PSMC3IP; TCERG1; BAZ1A; SMARCC1; NFE2L1; SREBF1; COPS2; HDGF; PTTG1; CTR9; PRPF6; NCOR2; TLE1; TAF10; HMGB1; TMF1; HMGB2; RNF10; C1QBP; DEK; HSF2; RERE; SIX2; MED1; REST; TSC22D2; ZNF32; GTF2IRD1; BRCA1; SIX1; TBPL1; IRF7; ZBTB38; SF1; NEDD8; HOXC10; TCF7L1; HOXB7; SUV39H1; TP53; TFAP2C; WWTR1; BTG1; EED; NR1D2; PBX3; HOXA5; HTATIP2; STAT1