Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID10226 Iniparib GSE70138 HA1E Human 24h 0.12uM EID0078
Types Number Response transcription factors
Up-regulation 15 RELB; BCL3; NFKB1; PPP1R13L; E2F5; HMGN3; ID1; KLF7; FOS; ID3; KLF5; MTA1; NFE2L2; RUNX3; FOXO1
Down-regulation 31 SAP30; TFAP2C; KLF1; NFAT5; NR1H4; PTTG1; CHD9; NANOG; NFE2; TOX3; BRD2; TOB1; ZNF217; ZNF652; SMAD7; NPM1; BTG1; IKBKAP; MYB; TBX3; CRYM; ZNF721; NR2F2; HOXB2; DACH1; NR4A2; HOXB6; MNDA; TXNIP; ST18; TP53