Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10161	Belinostat	GSE70138	HA1E	Human	24h	10uM	EID0077

Response Information :

Types	Number	Response transcription factors
Up-regulation	116	EGR1; NRBF2; KAT6B; PIAS1; RBBP5; NCOA3; EGR2; ZNF281; ADRB2; RCOR1; SNIP1; FOSB; HOXA5; HMG20B; YBX2; CITED2; DNAJC1; SND1; CTR9; BCL11B; JUNB; TCEB2; HSF2; RUNX3; NFIL3; PBXIP1; MED7; MAFB; CDK8; SETD3; CERS6; HEY2; MLXIP; PSPC1; RUVBL2; SERTAD2; STAT1; NR2C1; NFIB; CHD1; CUX1; HABP4; NOC2L; PEG3; MAF; ZNF331; IRF8; HDAC3; CREB3L2; CCNE1; TCF7L2; CBX6; SOX4; ARID4A; ISL1; CREM; TOB1; HDAC5; DBP; TCEA2; CDK2; HMGN3; MNAT1; NAB1; SPEN; ETV5; SMARCD3; SAP18; TAF12; ZKSCAN1; IKBKAP; TGFB1; MEF2A; FOXO4; HTATIP2; JARID2; INSR; CBX7; BRD2; FOXO3; NR0B1; NR4A2; NFATC1; FOXN3; STAT3; NR2F2; HIPK1; PHF20; BRD4; HDAC9; DLX2; TLE1; CRY1; HHEX; BMI1; FOXC1; OSR2; NFAT5; SPIB; KLF2; ID3; TRPS1; RHOA; LITAF; TSC22D1; CBFA2T3; FOS; TCF21; SATB2; ELF5; NRIP1; FLNA; CEBPB; ATF3; SOX11; ERBB2
Down-regulation	221	PAX8; FHL2; FOSL1; TGFB1I1; LOXL2; HDGF; BASP1; DEK; XBP1; PCBD1; PML; TEAD4; BCLAF1; RBM39; FOXM1; HMGB2; ZFY; HMGA2; MAFF; USP21; PMF1; ZNF33B; HOXB9; PITX2; CCNA2; DDX17; ECD; ZBED1; HIF1A; ZNF132; MAZ; HNRNPD; HOXB7; EMX2; BAZ1A; NFKBIA; RXRG; ING3; CTCF; IFI16; PRMT2; ATN1; MECOM; RAN; PATZ1; SMAD1; DNAJC2; SCMH1; KAT5; THAP4; GABPB1; BATF; SIX6; STAT6; TGIF1; CNOT2; SOX1; ATF1; SHOX; PRDM9; CTBP1; SOX17; KLF3; PRDM13; TAL1; CCDC59; AFF2; ASXL1; HMGB1; ZBTB7C; SIX3; CREB3L1; ZSCAN9; ZSCAN12; PSMC3; ZNF214; AIP; RELA; ARL2BP; NFKB1; HOXC4; PHF2; BTF3; CENPF; WHSC1; THRB; ELF4; BNC2; ZNF444; SMARCB1; ARNTL2; SOX14; ZMIZ1; SOX5; BPTF; VENTX; EWSR1; ACTL6A; AES; TULP3; BACH1; TEF; IRF2; GTF2I; ZHX2; WT1; DNMT1; TFCP2L1; PRDM1; POU6F2; ZNF580; ZFHX3; ID4; ZNF282; FOXJ1; BCL6; BHLHE40; HOXB2; CHD9; TCEA1; SP100; HOXB6; USP22; ZNF273; HOXD3; TBL1XR1; TAF9; APEX1; FOXL2; SALL1; CBFB; ZFP36L1; PLAG1; TFAP2C; RAD21; ZEB1; VGLL1; CREB1; TFEB; FOXG1; BAZ1B; NEUROG2; PRRX1; HOXC10; TRIM22; TFEC; GTF2IRD1; RNF138; KLF1; BNC1; POU2AF1; HOXB3; FOXA1; BARX1; TRIB3; SSX1; PCGF3; NEUROD1; NPM1; YBX3; KAT2B; KLF7; ZNF140; ZNF124; VEZF1; ARID5B; KLF4; ABL1; SLC2A4RG; FOXF2; FOXA2; TCF12; CRYM; NR2F6; REPIN1; RBPJ; NUP62; ZNF175; GRHL2; MYCN; SUV39H1; NKX3-1; VDR; ARID4B; ZNF467; INSM1; OLIG2; BCL11A; HOXB5; YEATS4; ST18; ZBTB38; TLE4; ESR1; TXNIP; MEIS2; MBD2; DLX5; PCGF2; EHF; SMAD3; SMAD7; TWIST1; NFE2; LMCD1; MYRF; TP63; ZNF217; LEF1; MEIS1; GTF3A; BHLHE41; ERBB4; ZNF91; ARNT2; TP53; PBX3; TRIM29; PAX6; MYBL1; ZNF274