Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID10137 I-bet-151 GSE70138 HA1E Human 24h 10uM EID0077
Types Number Response transcription factors
Up-regulation 90 SUZ12; HOXA5; PIAS1; HOXA10; LDB1; KAT6A; ARID1A; AFF1; CHD8; AATF; BRCA1; TRIM28; TRIM24; BRD2; ZNF131; MXD4; MYCBP; PSIP1; CUX1; NR2F2; YBX1; EP300; CDC5L; BRD4; SND1; HDAC4; NFIL3; PAX8; FOSB; POU2F1; ZKSCAN1; ZNF268; KMT2A; INSR; ZBTB48; IKBKAP; MAML1; PHF20; HMGA1; TCF25; ARNTL; CHD4; SMARCD3; HDAC1; RLF; DNMT1; SPEN; HHEX; EHMT2; MSX1; SCAND1; MAGED1; BTAF1; SFPQ; ZNF654; ZNF331; HMBOX1; TCF7; ZNF544; NR2C1; ENY2; OSR2; SREBF1; ARID4B; FOXO4; ZBTB16; PBX1; PEG3; ZNF274; FOXO3; CREB3L2; PHIP; CTR9; ID2; CBFA2T3; STAT3; YWHAB; SOX9; SOX4; STAT1; MAF; SPIB; ZFPM2; CTBP2; PURA; GATA6; SMAD3; IRF6; MYRF; ZBTB18
Down-regulation 86 FOSL1; MYC; NFKBIA; HES1; XBP1; CCNA2; MED21; FHL2; TGFB1I1; MAFF; PPP1R13L; IRF1; TWIST1; TSC22D3; BRD7; ACTL6A; ELK4; STAT6; CCDC59; MSC; BATF3; PTRF; PSMC3; MLLT10; ZFP36L1; C1D; TOX; TRIP6; ATF1; DDX17; CREB3L1; ERF; ARL2BP; IFI16; TBL1XR1; ZMYND11; TAL1; ZNF22; BACH1; NUP62; ISL1; TP63; EMX2; ZNF83; BIRC2; NR1D2; LOXL2; ID3; ZEB1; NKX2-2; ZNF32; ID4; LEF1; CBX3; LMCD1; NKX3-1; TBPL1; ERG; TCEA1; SUB1; ELK3; NFKB1; BASP1; BHLHE41; EGR2; SNAI2; BHLHE40; ELF5; POU2AF1; MAFB; RBPMS; HOXB7; KLF10; HIPK3; EHF; PITX1; KLF9; CALR; SPDEF; TRIM29; BMI1; ZBTB38; CREB1; ST18; MEIS2; ZIC1