Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID10114 I-bet-762 GSE70138 HA1E Human 24h 3.33uM EID0077
Types Number Response transcription factors
Up-regulation 55 PAX8; HOXA5; SAP130; ZNF331; HMGN3; EYA1; USP22; ZNF84; HDAC1; CITED2; HOXA11; RBBP7; HOXA10; TCEB2; SPEN; HSF2; ZNF131; TULP4; HEY1; MAGED1; CUX1; ZNF268; ZNF266; JARID2; DDIT3; HLTF; DNMT3B; NR4A1; IKBKAP; PAX5; ID1; FOSB; MAF; CTR9; WWTR1; SMAD3; PHIP; SOX4; TGFB1; NR2F2; STAT1; STAT3; TLE1; FLNA; NR4A2; TOB1; HOXC6; ZNF274; OSR2; ATF3; TXNIP; HHEX; ZNF589; SOX9; ZBTB18
Down-regulation 60 CRK; FOSL1; MAFF; NFKBIA; XBP1; TAF9; HMGA2; TGFB1I1; CNOT6; HDGF; ZNF189; PPRC1; HMGA1; NKX2-2; TFEC; TERF2; OLIG2; GATA4; SRF; KLF6; IRF1; KLF7; ATF4; ARNTL2; HOXB7; ZNF430; ZNF22; TAL1; EHF; LMCD1; HLX; HIPK3; NR1H3; ELF3; EGR2; TWIST1; HOXB2; MEOX1; CD3D; NEUROD1; MAFB; WT1; AEBP1; POU2AF1; SMAD1; ZEB1; ELK3; MECOM; TLE2; VDR; NFATC4; MYBL1; AHR; PAX6; ZBED2; HOXB6; ST18; GATA6; ESR1; RELB