Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID10027 Ku-60019 GSE70138 HA1E Human 24h 1.11uM EID0077
Types Number Response transcription factors
Up-regulation 187 HES1; ARID3A; NCOA3; CDX2; MAP3K10; INSM1; HDGF; KLF3; SSBP3; RBPJ; CITED2; MEIS2; SALL2; ZIC3; JUN; RBFOX2; ZXDC; SUPT3H; MDM2; PBX1; TAF1; EHMT2; FOXH1; TTF2; PRRX1; ZFPM2; NFIX; ZFP64; TAF4; NR5A2; NR0B2; ZNF117; MNDA; ERBB4; ZEB1; CBX6; FLI1; MECP2; HLX; TCEA2; CUX2; ZNF580; E2F8; ZNF33B; MDM4; SIX6; FOXA2; SKIL; TCF7L2; DNMT1; TRIP11; ASH1L; SRF; MED20; PNRC1; LHX3; ZIC1; ZNF93; KLF9; NR2C2; ETS2; CEBPD; ZSCAN31; CNOT2; TWIST1; EPAS1; ZNF141; EN1; NR4A3; ZNF43; NANOG; HMGA1; NKX2-1; EGR4; JAK2; AEBP1; BCL11A; ID4; LDB1; SPI1; FOXF1; ZNF124; NFIC; PRDM14; ZNF423; POU5F1B; RAD21; MEIS1; ZNF331; REL; PROX1; KLF4; ARID5B; IRF8; CBFA2T3; BRWD1; TFEC; ZNF232; ZNF217; NEUROD1; TP73; ZBTB16; FEZF2; EMX2; ELF4; SOX3; TDP2; CREM; MAFB; SOX11; ZNF665; CD3D; ZSCAN18; PBX3; FOXG1; PHIP; BARX1; ZNF544; HIPK2; KLF13; ASCL1; ATF6; ZNF467; ID1; GATA6; AR; HMBOX1; CBFA2T2; MECOM; RSF1; SOX2; LYL1; NR2F6; BCL6; MKL2; ZNF589; ZNF175; LIN28A; HIPK3; FOXF2; EHF; ISL1; ST18; HIRA; TCF7L1; TAL1; NFE2; ZNF573; BNC2; SOX17; MYCN; NR4A2; RBPMS; ZNF652; RXRA; NFATC4; PRDM2; OSR2; NR2F1; HIC2; MYCL; VPS72; ELF3; ATF3; ZNF22; NUP62; TOX; SSBP2; WWTR1; SNAI2; INSR; PEG3; YBX3; ZHX2; TCF21; IRF6; AHR; PAX6; KLF5; TP53; TRPS1; TFAP2C; ZNF91; HOXB2; ID3; MYB; KDM5D
Down-regulation 72 FHL2; NKX3-1; ADNP2; PCBD1; DAXX; TRIB3; HMGN3; RFX5; ELF1; ITGB3BP; HOXC6; NRBF2; PAX8; XBP1; SUB1; ZNF226; EYA2; SIM2; HSF2; SIX1; ELK3; NR2F2; NELFB; SMAD2; SP3; RBBP7; MBD2; ING3; CHD1; HDAC1; TFDP1; TRIM32; TSC22D2; ZNF593; PRKDC; CREB3L1; BBX; NFIB; TBL1X; NPAS2; BATF3; BIRC2; SOX10; ZNF131; RBBP4; ERBB2; ID2; PDLIM1; HOXA10; USF2; MAGED1; CBX3; CITED1; FOXD1; ZMYM2; MED1; ZBTB38; LEF1; ELF5; NR1H2; LMCD1; FOXJ3; PITX1; SOX9; EDF1; BHLHE41; CREG1; ERG; CTBP2; MSX1; HTATIP2; RELB