Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID10012	Mk-1775	GSE70138	HA1E	Human	24h	0.04uM	EID0077

Response Information :

Types	Number	Response transcription factors
Up-regulation	122	KDM5B; HDAC2; HMGB2; SNAI1; RBL2; NCOA4; HDGF; ORC2; CCNA2; ZNF556; UBP1; ARID1A; USF2; PKNOX1; CENPF; MEF2A; ENO1; RUVBL2; PPP1R13L; PA2G4; RHOA; MYOD1; MZF1; ATF7IP; HABP4; NELFB; CIC; TSC22D4; SSRP1; SETD3; CNOT1; MSC; STAT5B; CHD3; TRIM28; PTTG1; PPARD; PCGF2; CITED2; MNX1; ARNTL2; HMGN3; SMARCA2; POLR2A; RXRA; RBM14; CEBPZ; NR1H3; CREB1; KLF9; MAGED1; ZNF205; SMARCA1; ZKSCAN3; CALR; RORA; TADA3; HDAC7; SIX1; RERE; DBP; TGFB1; ZNF614; HNRNPD; WWTR1; GTF2IRD1; SSBP2; POU3F2; TFAM; AFF4; BCLAF1; NFKB1; AES; SF1; AGO2; BRD2; NEDD8; RFX7; CD3D; RBPJ; TBX21; JUP; AFF1; IRF4; MLXIPL; NR1D2; TRIM16; ZNF22; IRX5; FOXA2; POU4F1; FOXD1; EDF1; HIPK3; NFE2L2; NFAT5; YAP1; SMAD7; ETS2; CRY1; IL16; SMAD5; BARX1; NCOA1; BMI1; HOXA5; HMGB1; NR3C1; LITAF; NKX2-1; KDM5A; RELB; BCL3; BCL11B; ZSCAN18; KLF6; ERBB2; SSX1; NRIP1; KDM5D; ETV1; STAT1
Down-regulation	153	WWP1; EGR3; TBX3; PQBP1; PSMC3; ZNF107; JUN; MYBBP1A; HBP1; SUPT4H1; ZBTB20; ZMYND8; IFI16; ZNF492; COPS5; EP300; BHLHE41; TRIM29; NPAS2; CDK7; MAFF; ZBTB16; BACH2; TBX1; NCOA2; INSM1; ZNF267; CHD1; TCEA1; BCL10; TOX; ENY2; CUX2; TBL1XR1; ZNF24; PBX3; PRMT2; DNMT1; MED23; REL; NANOG; TAF9; CEBPB; PRRX1; SNAI2; BLZF1; ZKSCAN1; BRIP1; EGR2; ZNF12; SP140L; RBBP7; PATZ1; PLAGL1; FUBP1; SREBF1; NFKB2; CBX7; HEY2; BIRC2; SP110; ZNF268; TAF1A; BCL11A; TRPS1; ZNF200; ZNF273; TRIM22; PRDM10; HSF1; CBFA2T3; NR3C2; TFDP1; ATF1; ATF3; CCNH; KLF10; SP100; ZNF440; CUX1; ZFP36L2; PFDN5; TULP3; ST18; MITF; RNF138; TERF1; CTBP2; NFIB; PHF20; RREB1; ZNF264; SOX18; ZNF430; MKL2; ZNF652; ZNF623; TERF2; RUNX1; MTF2; NR2C1; CCNC; MED13; MYBL1; CITED1; ZNF217; AHR; ZNF611; TOB1; CREB3; SPDEF; TLE4; MXI1; NR2F2; PRDM2; TAL1; NKX3-1; ELF4; ZEB1; ID4; ESR1; SOX17; EMX2; TCF21; ZNF232; VPS72; TXNIP; NR2F6; RBBP8; NFE2L3; TRIB3; ZNF467; NFE2; ZFPM2; INSR; FOXJ3; KLF11; DACH1; PDLIM1; HHEX; WT1; PRKDC; ERG; ZBED2; MAF; HIC2; KLF4; SOX9; LEF1; MEIS1; ZNF91; GATA6; HOXB2