Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09875	Jq1-(+)	GSE70138	HA1E	Human	24h	3.33uM	EID0076

Response Information :

Types	Number	Response transcription factors
Up-regulation	147	KAT6A; HOXA5; SUZ12; PHF20; HOXB5; LDB1; EP300; HDAC5; TFDP2; DLX5; ZMYND8; MECP2; CBFA2T3; SMARCB1; POU2F1; HINFP; INSR; ZNF665; MED20; BCL11A; ZNF117; ZNF654; MMS19; ZNF3; KLF13; OSR2; ZFHX3; HOXA10; SOX3; CHD8; TERF2; BRD4; HOXB6; CBX6; ZBTB16; TERF1; ZBTB48; BTAF1; ZNF415; ATF3; SNAPC4; SPIB; ZNF331; ZNF324; NR2C1; ZNF274; ZNF606; LYL1; MTA1; HOXD1; SMAD1; IRF3; HHEX; PLAG1; ZNF544; POLR3C; PAXBP1; RBPJ; MKL2; CDC5L; CERS4; ZNF573; CBFA2T2; ZNF44; CITED2; PRDM10; PA2G4; ZNF131; CUX1; SOX2; MLXIP; PFDN5; CTBP2; ZNF688; HMBOX1; CDK9; ID1; TRIM24; TRIM28; FOXA2; ZNF467; ENY2; INSM1; PAX5; ELF4; NFATC4; CHD4; POU4F1; VPS72; ZSCAN18; JUP; TBL1X; LITAF; ZSCAN31; PGR; NKX2-1; NR5A2; E2F8; BRD2; DLX2; REL; CREM; TDP2; TCF7; NFIC; PEG3; AR; CCNH; MAF; HOXC4; YBX3; MYCL; HLX; MITF; ST18; ZKSCAN1; TSC22D1; BNC2; FOXO1; NFE2; GATA6; ZNF91; SREBF1; ESR1; TOB1; HMGN3; MYB; HEY1; SPDEF; HOXB7; TRIB3; NANOG; ERBB4; ZNF589; NEUROD1; ID2; HIC2; ZBTB18; FOXG1; TCF4; TXNIP; TOX; MEIS2; TCFL5; ZNF423; MYRF; ARNT2
Down-regulation	93	XBP1; FHL2; FOSL1; BASP1; SUB1; CCNA2; PCBD1; NFKBIA; GABPB1; TRIP6; URI1; HMGA2; ABL1; TGFB1I1; SUV39H1; MYC; ZBTB38; ELK3; BIRC2; PREB; TBL1XR1; NR1H2; ZMYND11; CCDC59; BMI1; CREB3L1; KLF2; PTRF; CBX3; ECD; TSC22D3; RFX5; REPIN1; MAX; TADA3; CRY1; JAK2; MBD2; TCF12; ZKSCAN7; ZNF32; EDF1; GTF2IRD1; SMARCA1; ZEB2; SMAD4; BHLHE41; EGR2; NKX3-1; IRF1; MAFB; ATF1; CBFB; PBX3; NELFB; CSDE1; ELF5; BCLAF1; MEIS1; BATF3; MED1; FLNA; RUNX1; LEF1; ZNF146; PITX1; FOXM1; HIPK3; DAXX; LMCD1; RBM14; BHLHE40; ZFP36L1; MTF2; SAP30; TRIM29; SOX9; ENO1; NR1D2; NPAS2; TRIM16; ETS1; NUP62; POU2AF1; SLC2A4RG; ZBED2; MNDA; HTATIP2; IFI16; EHF; TRIM22; NRIP1; STAT1